The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[1AS-13]【J】Chemical Homeostasis: Unraveling Cellular Homeostasis through Chemical Parameters

Wed. Dec 3, 2025 9:00 AM - 11:00 AM JST
Wed. Dec 3, 2025 12:00 AM - 2:00 AM UTC
Room 13(Pacifico Yokohama Conference Center 4F, 418)
Organizer: Ryo Ushioda (Kyoto Sangyo University), Keiko Kono (Okinawa Institute of Science and Technology Graduate University)
Cellular homeostasis possesses both the remarkable robustness and adaptable flexibility unique to life, exhibiting seemingly contradictory multifaceted characteristics. This intricate complexity makes understanding life even more challenging. This symposium aims to clarify the multifaceted nature of cellular homeostasis by leveraging the latest technologies, such as proteomic analysis, high-resolution electron microscopy, and deep learning based on chemical parameters. We will integrate chemical parameters across multiple levels, from molecules to organisms, and discuss their applications in aging and disease research.
9:00 AM - 9:02 AM JST(12:00 AM - 12:02 AM UTC)

Introduction

9:02 AM - 9:17 AM JST(12:02 AM - 12:17 AM UTC)

[1AS-13-01]Proteostasis and Stress Responses Orchestrated by the Redox Environment of the Endoplasmic Reticulum

○Ryo Ushioda1,2 (1. Faculty of Life Sci., Kyoto Sangyo Univ., 2. Institute of Protein Dynamics., Kyoto Sangyo Univ.)
Comment()
9:17 AM - 9:32 AM JST(12:17 AM - 12:32 AM UTC)

[1AS-13-02]Activation of Golgi stress response triggered by PI4P homeostasis disruption and its functional role

○Kanae Sasaki1, Hiderou Yoshida1 (1. University of Hyogo)
Comment()
9:32 AM - 9:47 AM JST(12:32 AM - 12:47 AM UTC)

[1AS-13-03]Unique metabolism and its regulation in hyperthermophilic archaea

○Haruyuki Atomi1 (1. Kyoto University)
Comment()
9:47 AM - 10:00 AM JST(12:47 AM - 1:00 AM UTC)

[1AS-13-04(1P-906)]Stoichiometric Coordination of Coenzymes and Enzymes as a Basis for Intracellular Homeostasis

○Yasushi Kojima1, Emi Mishiro2, Teruaki Fujishita1, Rie Kajino1, Tomoyoshi Soga3, Masahiro Aoki1,4 (1. Aichi Cancer Center, 2. Nagoya Univ. WPI-ITbm, 3. Keio Univ., 4. Nagoya Univ.)
Comment()
10:00 AM - 10:15 AM JST(1:00 AM - 1:15 AM UTC)

[1AS-13-05]Multiaxial proteome analysis for comprehensive understanding of chemical parameter perturbations

○Masaki Matsumoto1 (1. Niigata University)
Comment()
10:15 AM - 10:28 AM JST(1:15 AM - 1:28 AM UTC)

[1AS-13-06(1P-879)]Identification of human serum proteins related to incidence and survival time of pancreatic cancer using exploratory proteomics

○Yuji Iwashita1, Yuriko Koyanagi1, Yumiko Kasugai1, Isao Oze2, Issei Imoto3, Hidemi Ito2, Keitaro Matsuo1 (1. Div. Cancer Epidemiol. Prev., Aichi Cancer Ctr. Res. Inst., 2. Div. Cancer Ctrl. Info., Aichi Cancer Ctr. Res. Inst., 3. Aichi Cancer Ctr. Res. Inst.)
Comment()
10:28 AM - 10:43 AM JST(1:28 AM - 1:43 AM UTC)

[1AS-13-07]Regulation of ER–Mitochondria Contact Sites by the Intrinsically Disordered Region of PDZD8

Takahiro Nagao1, Christian Hoffmann2, Taka A. Tsunoyama3, Koki Nakamura1, Saeko Aoyama-Ishiwatari1, Akihiro Kusumi3, Dragomir Milovanovic2, ○Yusuke Hirabayashi1 (1. The University of Tokyo, 2. German Center for Neurodegenerative Diseases , 3. OIST)
Comment()
10:43 AM - 10:58 AM JST(1:43 AM - 1:58 AM UTC)

[1AS-13-08]Chemical Atlas Perturbation Links Plasma Membrane Damage to Cellular Senescence

○Keiko Kono Kono1 (1. Okinawa Institute of Science and Technology Graduate University)
Comment()
10:58 AM - 11:00 AM JST(1:58 AM - 2:00 AM UTC)

Conclusion

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