Session Details
[1PS-13]【E】How to use RNA : Expanding Molecular Machineries Through RNA Exaptation
Wed. Dec 3, 2025 2:20 PM - 4:20 PM JST
Wed. Dec 3, 2025 5:20 AM - 7:20 AM UTC
Wed. Dec 3, 2025 5:20 AM - 7:20 AM UTC
Room 13(Pacifico Yokohama Conference Center 4F, 418)
Organizer: Shinichi Nakagawa (Hokkaido University), Hazuki Takahashi (RIKEN)
During evolution, organisms repurpose “junk" RNAs, forging novel molecular machinery surpassing protein-only capabilities. This symposium explores large-scale screening to uncover hidden functional lncRNAs, physiological studies using mutant mice to validate their roles, and structural analyses that reveal mechanistic detail—showcasing how RNA exaptation fuels groundbreaking molecular innovation.
Introduction
[1PS-13-01]Rheostat-like function of a long noncoding RNA involved in a rare lung disease
○Martin Sauvageau1 (1. Montreal Clinical Research Institute (IRCM), Canada)
[1PS-13-02]LncRNA-mediated local regulation of RNA helicase activity
○Miho M Suzuki1, JIngqi Xie1, Keiko Shinjo1, Nishimura Tatsunori1, Yutaka Kondo1 (1. Nagoya University Graduate School of Medicine)
[1PS-13-03(1P-161)]Block Copolymer Micellization: A Novel Design Principle for RNA-Protein Complex Assembly
○Tomohiro Yamazaki1,2, Ichiro Taniguchi1, Tetsuya Yamamoto3, Sylvie Souquere4, Sota Umezaki1, Shinichi Nakagawa5, Gerard Pierron4, Tetsuro Hirose1,2,6 (1. FBS, The Univ. of Osaka, 2. Grad. Sch. Sci., The Univ. of Osaka, 3. ICReDD, Hokkaido Univ., 4. CNRS, 5. Pharm. Sci., Hokkaido Univ., 6. OTRI, The Univ. of Osaka)
[1PS-13-04]The quiet power of long non-coding RNA ”SINEUP” in protein synthesis
○Hazuki Takahashi1, Piero Carninci1,2 (1. RIKEN, 2. Human Technopole)
[1PS-13-05(1P-176)]Functional Analysis of Core tRNA Modifications Using an E. coli 11KO Model
○Karolina Honzejkova1, Gen-Ichiro Uechi1, Paola Laurino1,2 (1. Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Japan, 2. Institute for Protein Research, Osaka University, Suita, Japan)