The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[1PS-14]【J】An integrated understanding of “tissue vascularization" by the collaboration of chemistry, biology, engineering and medicine

Wed. Dec 3, 2025 2:20 PM - 4:20 PM JST
Wed. Dec 3, 2025 5:20 AM - 7:20 AM UTC
Room 14(Pacifico Yokohama Conference Center 4F, 419)
Organizer: Ken-ichi Mizutani (Kobe Gakuin University), Hiroko Ishii-Shimada (Keio University)
Blood vessel functions as a network to integrate all tissues, such as maintaining homeostasis and organogenesis, and plays an important role in tissue regeneration. In this symposium, we will share the latest findings on tissue vascularization from the perspectives of developmental biology, material chemistry, engineering, and pathology by integrating the concepts of each field, and develop a broad discussion on the diverse biology governed by vascularization.
2:20 PM - 2:24 PM JST(5:20 AM - 5:24 AM UTC)

Introduction

2:24 PM - 2:40 PM JST(5:24 AM - 5:40 AM UTC)

[1PS-14-01]Aggrecan-type proteoglycan in tissue vascularization

○Ken-ichi Mizutani1 (1. Kobe Gakuin Univ.)
Comment()
2:40 PM - 2:56 PM JST(5:40 AM - 5:56 AM UTC)

[1PS-14-02]Vascular structures regulating microglial colonization in the brain

○Yuki Hattori1 (1. Nagoya University)
Comment()
2:56 PM - 3:12 PM JST(5:56 AM - 6:12 AM UTC)

[1PS-14-03(1P-569)]The Notch–TGFβ2 axis mediates endothelial–pericyte interaction to promote angiogenesis via enhancing type 4 collagen vascular basement membrane formation.

○semanti Halder1, Honami Ogo1, Yasuyuki Hanada1, Vishnuvardhinidutt Kasi1, Yuka Ozeki1, Katarzyna Anna Inoue2, Miho Kobayashi2, Tetsuro Watabe2, Akiyoshi Uemura3, Koichi Nishiyama1 (1. Lab. for Vasc. and Cell. Dyn., Fac. of Medicine, Univ. of Miyazaki, 2. Dept. of Biochem., Grad. Sch. of Med. and Dent. Sci., Tokyo Med. and Dent. Univ. , 3. Dept. of Retinal Vasc. Biol., Nagoya City Univ. Grad. Sch. of Med. Sci.)
Comment()
3:12 PM - 3:28 PM JST(6:12 AM - 6:28 AM UTC)

[1PS-14-04]Development of astrocyte-enriched cortical organoids containing functional astrocytes that promote synaptogenesis and contribute to blood-brain barrier formation.

○Hiroko Shimada1, Hideyuki Okano1 (1. Keio Univ. Regenerative Medicine Research Center)
Comment()
3:28 PM - 3:44 PM JST(6:28 AM - 6:44 AM UTC)

[1PS-14-05]The Role of Vascular Endothelial Growth Factor (VEGF) in Functional Recovery After Ischemic Stroke.

○Itsuki Ajioka1 (1. Institute of Science Tokyo)
Comment()
3:44 PM - 4:00 PM JST(6:44 AM - 7:00 AM UTC)

[1PS-14-06(1P-763)]Development of Anti-Sepsis Drug Focusing on Vasoprotective Activities of High-Density Lipoprotein

○Reina Nakanishi1, Tatsuya Murakami1,2 (1. Toyama Prefectural Univ., 2. Kyoto Univ.)
Comment()
4:00 PM - 4:16 PM JST(7:00 AM - 7:16 AM UTC)

[1PS-14-07]Development of fundamental technologies for vascular microphysiological systems (MPS) and their application to three-dimensional culture

○Ryuji Yokokawa1 (1. Kyoto University)
Comment()
4:16 PM - 4:20 PM JST(7:16 AM - 7:20 AM UTC)

Conclusion

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