The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Mini-Symposia

[1MS-03]【J】Molecular Modification Produces Regulation of Biological Functions and Diseases

Wed. Dec 3, 2025 11:15 AM - 12:35 PM JST
Wed. Dec 3, 2025 2:15 AM - 3:35 AM UTC
Room 3(Pacifico Yokohama Conference Center 3F, 302)
Organizer: Masamitsu Konno (National Institute of Advenced Industrial Science and Technology), Keisuke Hitachi (Fujita Health University)
Various biomolecules, such as DNA, RNA, and proteins, undergo modifications that regulate their functions. These molecular modifications contribute to various life phenomena and even to the development and malignant effects of various diseases. In this symposium, we will present cutting-edge research results related to molecular modifications by young researchers. This will deepen understanding of the importance of molecular modifications in biological processes and encourage new players to start their research in this field.
11:15 AM - 11:26 AM JST(2:15 AM - 2:26 AM UTC)

[1MS-03-01]Regulation of skeletal muscle myosin heavy chain activity via the protein methylation

○Keisuke Hitachi1 (1. Div. for Thera. Intract. Dis., CMS, Fujita Health Univ.)
Comment()
11:26 AM - 11:37 AM JST(2:26 AM - 2:37 AM UTC)

[1MS-03-02]Regulatory mechanisms of cardiac remodeling via arginine methylation

○Yasufumi Katanasaka1,2,3 (1. University of Shizuoka, 2. NHO Kyoto Med. Centr., 3. Shizuoka General Hosp.)
Comment()
11:37 AM - 11:44 AM JST(2:37 AM - 2:44 AM UTC)

[1MS-03-03(1P-277)]Proteome-wide Correlation between Protein Half-Life and N-Terminal Acetylation by Bottom-up Proteomics

○Akane Takeshita1, Eisuke Kanao1,2, Koshi Imami3, Yasushi Ishihama1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. NIBIOHN, 3. IMS, RIKEN)
Comment()
11:44 AM - 11:51 AM JST(2:44 AM - 2:51 AM UTC)

[1MS-03-04(1P-885)]Disrupting Pancreatic Cancer Metabolism Through Chemically Modified-Glutamine-Mediated Glutamine Antagonism

○Bo Xu1, Chisato Iwabuchi1, Manami Hasegawa2, Honoka Imagawa2, Miyuki Nishida1, Tsuyoshi Osawa1,2,3 (1. Division of Integrative Nutriomics and Oncolygy, RCAST, the University of Tokyo, 2. Department of Chemistry and Biotechnology, Faculty of Engineering, the University of Tokyo, 3. Department of Biological Sciences, Graduate School of Science, the University of Tokyo)
Comment()
11:51 AM - 11:58 AM JST(2:51 AM - 2:58 AM UTC)

[1MS-03-05(1P-079)]Physiological effects of different types DNA modifications induced by an acrylamide metabolite

○Jun-ichi Akagi1, Masayuki Yokoi2, Yumi Miyake3, Kohei Matsushita1, Kaoru Sugasawa2, Shigenori Iwai2,4,5, Takeshi Toyoda1 (1. Div. Pathology, Natl. Inst. Health Sci., 2. Biosignal Res. Ctr., Kobe Univ., 3. Forefront Res. Ctr., Grad. Sch. of Sci., Osaka Univ., 4. Grad. Sch. of Eng. Sci., Osaka Univ., 5. Frontier Science, Konan Univ.)
Comment()
11:58 AM - 12:09 PM JST(2:58 AM - 3:09 AM UTC)

[1MS-03-06]Functional Role of m6A RNA Methylation in Colorectal Cancer Progression

○Yuki Kuwano1, Hiroyuki Morino1 (1. Tokushima University Graduate School)
Comment()
12:09 PM - 12:16 PM JST(3:09 AM - 3:16 AM UTC)

[1MS-03-07(1P-789)]Meta-analysis of RNA modification-related genes in HTLV-1 -infected cells

○Rei Gibu1,2, Kodai Gibu3,4, Yuko Aihara2, Motomi Yamazaki2, Makoto Yamagishi1, Masamitsu Konno2,5,6,7 (1. UTokyo GSFS, 2. AIST CMB, 3. UTokyo GSALS, 4. AIST GSJ, 5. The Univ. of Osaka, 6. YCU, 7. TUS)
Comment()
12:16 PM - 12:24 PM JST(3:16 AM - 3:24 AM UTC)

[1MS-03-08(1P-114)]Relationship between neurodegenerative diseases and FUS as a novel m6A reader

○Ryoma YONEDA1, Naomi UEDA1, Riki KUROKAWA1 (1. Dept. of Biol. Sci., Faculty of Med., Saitama Med. Univ.)
Comment()
12:24 PM - 12:35 PM JST(3:24 AM - 3:35 AM UTC)

[1MS-03-09]Comprehensive RNA modification analysis to reveal the mechanisms of cancer progression and develop medical applications

○Masamitsu Konno1,2,3,4 (1. AIST, 2. Osaka University, 3. Tokyo University of Science, 4. Yokohama City University)
Comment()
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