[1MS-04] 【J】Molecular Biology of The Gap | The 48th Annual Meeting of the Molecular Biology Society of Japan

Session Details

Mini-Symposia

[1MS-04]【J】Molecular Biology of The Gap

Wed. Dec 3, 2025 11:15 AM - 12:35 PM JST
Wed. Dec 3, 2025 2:15 AM - 3:35 AM UTC

Room 4(Pacifico Yokohama Conference Center 3F, 303)

Organizer: Junko Murai (Ehime University), Satoshi Nakata (Gunma University)

Organisms detect and repair gaps across various biological contexts, such as single-stranded DNA gaps during replication or tissue gaps from cell removal. However, some gaps remain unrecognized. In this symposium, we introduce “Gap Molecular Biology," exploring conserved mechanisms of gap recognition and repair across different cell systems, and we discuss their broader biological significance.

11:15 AM - 11:30 AM JST(2:15 AM - 2:30 AM UTC)

[1MS-04-01]Biology of DNA Gaps: How do cells manage single-stranded DNA gaps?

○Junko Murai¹ (1. Proteo-Science Center, Ehime University)

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11:30 AM - 11:43 AM JST(2:30 AM - 2:43 AM UTC)

[1MS-04-02]Histone homeostasis mechanisms preventing chromatin gaps and the effects of their collapse

○Keiichi Izumikawa¹, Tatsuya Shida¹, Masami Nagahama¹ (1. Meiji Pharmaceutical University)

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11:43 AM - 11:56 AM JST(2:43 AM - 2:56 AM UTC)

[1MS-04-03]Sensing and regulation of intercavitary spaces

○Tomohisa Sakaue¹ (1. Ehime University)

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11:56 AM - 12:09 PM JST(2:56 AM - 3:09 AM UTC)

[1MS-04-04(1P-062)]The genetic interaction between Polη and Polζ differs between “on the fly” TLS and TLS in “post replicative gap filling”

○Mone Okuda¹, Minori Fujii¹, Ryotaro Kawasumi¹, Kouji Hirota¹ (1. Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University)

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12:09 PM - 12:22 PM JST(3:09 AM - 3:22 AM UTC)

[1MS-04-05(1P-572)]Analysis of cell dynamics regulated by a novel bleb-like structure dependent on planar cell polarity

○Minako Suzuki¹, Shinji Takada², Yusuke Mii¹ (1. Kyoto Univ., 2. NIBB)

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12:22 PM - 12:35 PM JST(3:22 AM - 3:35 AM UTC)

[1MS-04-06]Astrocyte-Mediated Extracellular Space Maintenance and Homeostasis in the Brain Microenvironment

○Satoshi Nakata¹ (1. Department of Neurosurgery, Gunma University)

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