The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[1PS-07]【J】The Spatiotemporal Order of Collective Cell Migration

Wed. Dec 3, 2025 2:20 PM - 4:20 PM JST
Wed. Dec 3, 2025 5:20 AM - 7:20 AM UTC
Room 7(Pacifico Yokohama Conference Center 3F, 313+314)
Organizer: Koji Tsutsumi (Kitasato University), Mikiko Inaki (University of Hyogo)
Collective cell migration occurs during the processes of self-organization of cells, such as development, regeneration, and cancer metastasis. The order emerges in the collective cell migration through the spatiotemporal regulation of signal transduction, cell adhesion, and mechanical interactions, but the overall mechanism remains unclear. This symposium will present the latest findings from mathematical models and 3D imaging and discuss future research directions.
2:20 PM - 2:32 PM JST(5:20 AM - 5:32 AM UTC)

[1PS-07-01]RacGAP-mediated Tuning of YAP Activity Controls Collective Epithelial Migration

○Koji Tsutsumi1 (1. Kitasato University)
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2:32 PM - 2:50 PM JST(5:32 AM - 5:50 AM UTC)

[1PS-07-02]Wounding induces preexisting multinucleated cells to survive and thrive as leader cells

○Yuta Takahashi1, Kenji Matsuzawa1, Junichi Ikenouchi1 (1. Kyushu University)
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2:50 PM - 3:08 PM JST(5:50 AM - 6:08 AM UTC)

[1PS-07-03]Single-molecule imaging analysis of anterior-posterior polarity formation by Ras in eukaryotic migrating cells

○Satomi Matsuoka1, Koji Iwamoto1, Masahiro Ueda1 (1. The University of Osaka)
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3:08 PM - 3:20 PM JST(6:08 AM - 6:20 AM UTC)

[1PS-07-04]Collective cell behavior drives left-right asymmetric rotation of the Drosophila hindgut.

○Mikiko Inaki1,2, Yugo Minami2, Takamichi Sushida3, Masakazu Akiyama4, Yasuhiro Inoue5, Kenji Matsuno2 (1. Dept. Life Sci., Grad. Sch. Sci., Hyogo Univ., 2. Dept. Biol., Grad. Sch. Sci. Osaka Univ., 3. Fukuchiyama Univ., 4. Dept. Math, Grad. Sch. Sci., Toyama Univ., 5. Microeng., Grad. Sch. Eng., Kyoto Univ)
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3:20 PM - 3:38 PM JST(6:20 AM - 6:38 AM UTC)

[1PS-07-05]Shaping the embryonic axis in zebrafish: Coordinated growth of multiple tissues via collective cell migration

○Toru Kawanishi1, Takamichi Sushida2, Tony Y.-C. Tsai3, Hiroyuki Takeda4, Sean G. Megason5 (1. Institute of Science Tokyo, 2. University of Fukuchiyama, 3. Washington University School of Medicine, St. Louis, 4. Kyoto Sangyo University, 5. Harvard Medical School)
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3:38 PM - 3:56 PM JST(6:38 AM - 6:56 AM UTC)

[1PS-07-06]A cell membrane model that reproduces cortical flow-driven cell migration and collective movement

○Katsuhiko Sato1 (1. University of Toyama)
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3:56 PM - 4:08 PM JST(6:56 AM - 7:08 AM UTC)

[1PS-07-07(1P-410)]Spontaneous pattern formation through cell migration organized by extracellular matrix-producing chondrocytes

○Shogo Nakayama1, Masahito Mori2, Keishi Kishimoto1, Kyosuke Adachi1, Takumi Matsuura1, Kyogo Kawaguchi3,4, Mitsuru Morimoto1 (1. RIKEN BDR, 2. Department of Physics, University of Tokyo, 3. RIKEN Cluster for Pioneering Research, 4. Institute for Physics of Intelligence, University of Tokyo)
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4:08 PM - 4:20 PM JST(7:08 AM - 7:20 AM UTC)

[1PS-07-08(1P-565)]Removal of the lens capsule, an exceptionally thick basement membrane, unleashes robust contraction of the epithelial sheet

○Yuki Sugiyama1 (1. Yokohama City Univ.)
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