Session Details
[1AS-08]【J】Advancing genome biology through functional genomics data and databases
Wed. Dec 3, 2025 9:00 AM - 11:00 AM JST
Wed. Dec 3, 2025 12:00 AM - 2:00 AM UTC
Wed. Dec 3, 2025 12:00 AM - 2:00 AM UTC
Room 8(Pacifico Yokohama Conference Center 3F, 315)
Organizer: Hideya Kawaji (Tokyo Metropolitan Institute of Medical Science)
The understanding of our genome has been rapidly advancing, covering genome diversity, epigenome, and transcriptome. This advancement is driven by cutting-edge technologies and foundational databases. We aim to discuss about the recent developments in this domain and the genomic insights derived from recent studies.
Introduction
[1AS-08-01]Functional Characterization of human genetic variants using Massively Parallel Reporter Assay
○Kousuke Mouri1, Ryan Tewhey1 (1. The Jackson Laboratory)
[1AS-08-02]Exploring the Functional Roles of the Non-Coding Genome as the Next Target in Mouse Phenotype Analysis
○Naoki Kubo1, Akiko Oguchi2,3, Hiroshi Masuya1, Takanori Amano1, Hideya Kawaji4, Takeya Kasukawa2, Shinya Oki5, Toyoyuki Takada1, Kimiko Inoue1, Atuo Ogura1, Yasuhiro Murakawa2,3, Masaru Tamura1, Atsushi Yoshiki1, Toshihiko Shiroishi1 (1. RIKEN BioResource Research Center, 2. RIKEN Center for Integrative Medical Sciences, 3. Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University , 4. Tokyo Metropolitan Institute of Medical Science, 5. Institute of Resource Development and Analysis, Kumamoto University)
[1AS-08-03]Drug-induced cis-regulatory elements in human hepatocytes affect molecular phenotypes associated with adverse reactions
○Saki Saito1, Ryoko Wada1, Tomoe Nishimura2, Hideya Kawaji1 (1. Res. Ctr. Genome. Med. Sci., TMiMS , 2. CBRT, TMiMS)
[1AS-08-04]Systematic development of a splice-site creating variant registry using massive public transcriptome data
○Naoko Iida1, Ai Okada2, Yoshihisa Kobayashi3, Kenichi Chiba2, Yasushi Yatabe3, Yuichi Shiraishi2 (1. Transl. Res. Support Off., NCCE, 2. Genome Analysis Platform Dev., NCCRI, 3. Div. Molecular Pathology, NCCRI)
[1AS-08-05(1P-893)]Identification and functional analysis of germline mutations associated with recurrence in colorectal cancer
○Masaki Ohira1,2, Yoshiaki Nakamura3, Masao Nagasaki4,5, Takao Fujisawa3, Tadayoshi Hashimoto3, Jun Watanabe6, Saori Mishima7, Hiromichi Ebi8, Hideaki Bando3, Ichiro Takemasa9, Takeshi Kato10, Daisuke Kotani7, Eiji Oki11, Takayuki Yoshino7, Katsuya Tsuchihara1,2, Riu Yamashita1,12 (1. Division of Translational Informatics, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 2. Department of Integrated Biosciences, Graduate school of Frontier Sciences, The University of Tokyo, 3. Translational Research Support Office, National Cancer Center Hospital East, 4. Division of Biomedical Information Analysis, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 5. Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, 6. Department of Colorectal Surgery, Kansai Medical University, 7. Department of Gastrointestinal Oncology, National Cancer Center Hospital East, 8. Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, 9. Department of Gastroenterological Surgery, Osaka International Medical & Science Center, 10. Department of Surgery, NHO Osaka National Hospital, 11. Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 12. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo)
[1AS-08-06(1P-003)]Systematic analysis of novel heat stress-related long non-coding RNAs through FANTOM6 datasets and meta-analysis of public transcriptome data
○Sora Yonezawa1, Takeya Kasukawa2,3, Hidemasa Bono1,3 (1. Hiroshima Univ., 2. RIKEN IMS, 3. HUGE)
[1AS-08-07(1P-570)]Understanding the molecular mechanisms controlling body color of ornamental teleost fish strains (Oryzias latipes and Cyprinus carpio)
○Yoshihiro Omori1,2, Tetsuo Kon3, Rui Tang2, Koto Kon-Nanjo3, Soichiro Fushiki2, Soma Tomihara1,2, Yusuke Takehana2, Atsushi Toyoda 4, Hideki Noguchi4,5, Kohji Mabuchi6, Kiyoshi Naruse7 (1. Graduate School of Integrated Sciences for Life, Hiroshima University, 2. Graduate School of Bioscience, Nagahama Institute of Bioscience and Technology, 3. Department of Neurosciences and Developmental Biology, University of Vienna, 4. National Institute of Genetics, 5. Center for Genome Informatics, ROIS-DS, 6. National Institute for Environmental Studies, 7. National Institute for Basic Biology)