The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[2PS-11]【J】Advances in Structural Life Science: From Dynamics to In Situ

Thu. Dec 4, 2025 2:20 PM - 4:20 PM JST
Thu. Dec 4, 2025 5:20 AM - 7:20 AM UTC
Room 11(Pacifico Yokohama Conference Center 4F, 414+415)
Organizer: Hiroshi Nishimasu (The University of Tokyo), Hideaki Kato (The University of Tokyo)
Advancements in cryo-electron microscopy (cryo-EM) have enabled us to understand biological processes at the atomic level and design proteins not found in nature. This workshop will present and discuss cutting-edge research achievements, focusing on cryo-EM structural analysis of proteins and nucleic acids, and the development of novel proteins using these innovative technologies
2:20 PM - 2:23 PM JST(5:20 AM - 5:23 AM UTC)

Introduction

2:23 PM - 2:43 PM JST(5:23 AM - 5:43 AM UTC)

[2PS-11-01]Activating and inhibiting nucleotide signals coordinate bacterial anti-phage defense

○Sonomi Yamaguchi1,2, Samantha G. Fernandez1,2, Douglas R. Wassarman1,3, Marlen Lüders3, Frank Schwede3, Philip J. Kranzusch1,2,4 (1. Dana-Farber Cancer Institute, 2. Harvard Medical School, 3. Biolog Life Science Institute GmbH & Co. KG, 4. Parker Institute for Cancer Immunotherapy at Dana-Farber Cancer Institute)
Comment()
2:43 PM - 2:58 PM JST(5:43 AM - 5:58 AM UTC)

[2PS-11-02(2P-129)]Structural analysis of RNA polymerase II transcribing chromatin by ChIP-cryoEM

○Tomoya Kujirai1,2, Junko Kato1, Kyoka Yamamoto1, Seiya Hirai1, Lumi Negishi1, Mitsuo Ogasawara1, Yuki Yamaguchi3, Yoshimasa Takizawa1, Hitoshi Kurumizaka1,2 (1. Univ. Tokyo, 2. RIKEN, 3. Sci. Tokyo)
Comment()
2:58 PM - 3:18 PM JST(5:58 AM - 6:18 AM UTC)

[2PS-11-03]Discovery of PyShell, that shapes diatom chloroplasts; structure and function

○Yusuke Matsuda1, Ginga Shimakawa2, Akihiro Kawamoto3, Hiroaki Matsui1, Genji Kurisu3 (1. Kwansei Gakuin University, 2. Kobe University, 3. Osaka University)
Comment()
3:18 PM - 3:38 PM JST(6:18 AM - 6:38 AM UTC)

[2PS-11-04]Conformational dynamics governing G-protein activation by Neurotensin Receptor 1

○Hideaki Kato1 (1. The University of Tokyo)
Comment()
3:38 PM - 3:58 PM JST(6:38 AM - 6:58 AM UTC)

[2PS-11-05]A newly discovered multi-subunit sperm fertilization complex regulates vertebrate fertilization

○Andrea Pauli1, Victoria Deneke1, Johannes Suwita1, Shingo Tonai2, Yonggang Lu3, Karin Panser1, Masahito Ikawa2 (1. IMP, Vienna BioCenter, Vienna, Austria, 2. Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan, 3. Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Osaka 565-0871, Japan)
Comment()
3:58 PM - 4:18 PM JST(6:58 AM - 7:18 AM UTC)

[2PS-11-06]Structural basis for DNA/RNA transport across the biological membrane

○Osamu Nureki1, kaoru Kumazaki1, Tsukasa Kusakizako1, Hisato Hirano1, Akira Takai1, Yasushi Okada1 (1. The University of Tokyo)
Comment()
4:18 PM - 4:20 PM JST(7:18 AM - 7:20 AM UTC)

Conclusion

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