Session Details

[2PS-14]【E】Design and control of biomimetic system for multicellualr organization

Thu. Dec 4, 2025 2:20 PM - 4:20 PM JST
Thu. Dec 4, 2025 5:20 AM - 7:20 AM UTC
Room 14(Pacifico Yokohama Conference Center 4F, 419)
Organizer: Masaya Hagiwara (RIKEN), Ayae Narutaki (Institute of Science Tokyo)
Cells receive spatial information from mechanical and chemical signals in their environment and construct multicellular systems. Technologies that artificially manipulate the in-vitro environment are extremely useful in elucidating and reconstructing these systems. On the other hand, effective utilization of these techniques requires a thorough understanding of the systems and essential design and control of the environment. This symposium aims to explore new experimental systems by discussing technologies for manipulating environments, such as materials and devices, with molecular biology researchers.

Introduction

[2PS-14-01]Engineering Spatiotemporal Microenvironments to Guide Neural Tube Organoid Morphogenesis

○Masaya Hagiwara1, Yuriko Laura Teshima1,2, Saw Marlar1 (1. RIKEN BDR, 2. Kyoto Univ.)
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[2PS-14-02]Stage-specific manipulation of tissue shape enables directed modulation of cell fate

○Satoru Okuda1 (1. Kanazawa University)
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[2PS-14-03]Modeling Human Embryo Implantation and Placental Development through Biophysical Microenvironment Design

○Shun Shibata1 (1. Tohoku Univertsity Graduate School of Medicine)
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[2PS-14-04]Development and Functional Characterization of Elastin-Inspired Designer Matrices

○Ayae Sugawara-Narutaki1 (1. Institute of Science Tokyo)
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[2PS-14-05]The epidermal stem cell supporting matrix fibulin 7 modulates skin inflammatory response in a psoriasis model

○Erna Raja1, Tomoko Machida1, Karolina Edlund2, Narenmandula Narenmandula1, ASM Sakhawat1, Jun Tsunezumi3, Yukihide Watanabe4, Ken Natsuga5, Kenichi Kimura1, Aiko Sada6, Hiromi Yanagisawa1 (1. Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan, 2. Leibniz Research Center for Working Environment and Human Factors, Dortmund University, Germany, 3. Department of Pharmacy, Kyushu University of Health and Welfare, Japan, 4. Institute of Medicine, University of Tsukuba, Japan, 5. Department of Dermatology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan, 6. Medical Institute of Bioregulation, Kyushu University, Japan.)
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Conclusion