Session Details

[2MS-02]【J】Multicellular Dynamics Driven by Cell-Cell Interactions

Thu. Dec 4, 2025 11:15 AM - 12:35 PM JST
Thu. Dec 4, 2025 2:15 AM - 3:35 AM UTC
Room 2(Pacifico Yokohama Conference Center 3F, 301)
Organizer: Koji Kikuchi (Kumamoto University), Yusuke Mii (Kyoto University)
Tissue structures arise from multicellular dynamics, including morphological changes, migration, and differentiation, guided by tissue-specific developmental programs. These dynamics are driven by biochemical signals and mechanical cues mediated via cell-cell interactions. However, their molecular mechanisms and the diseases caused by their disruption remain unclear. This symposium highlights the latest research on the molecular basis of multicellular dynamics and their role in disease onset.

[2MS-02-01]Reconstruction of planar cell polarity (PCP) with cultured cells and physiological roles of "unpolarized" PCP components.

○Yusuke Mii1, Soichi Matsuo1, Minako Suzuki1, Sayuki HIrano2, Mikio Furuse3, Shinji Takada4, Kazuhiro Aoki2, Mototsugu Eiraku1, Tetsuhisa Otani5 (1. LiMe, Kyoto Univ., 2. Grad. Sch. Biostudies, Kyoto Univ., 3. NIPS, 4. NIBB, 5. Tokyo Metropolitan Univ.)
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[2MS-02-02]Bilateral cellular flows during avian gastrulation exhibit left–right asymmetry

○Rieko Asai1 (1. Kumamoto University)
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[2MS-02-03]Molecular mechanisms of neural tube closure driven by surface ectoderm cells

○Isao Matsuo1, Chiharu Kimura-Yoshida1 (1. Osaka Women's and Children's Hospital)
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[2MS-02-04]Elucidation of morphogen gradient correction mechanisms driven by mechano-chemical crosstalk

○Kana Aoki1, Tohru Ishitani1 (1. Dept. of Homeostatic Regulation, RIMD, The University of Osaka)
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[2MS-02-05]MAP7-driven cytoskeletal cross-talk establishes Sertoli cell polarity critical for germ cell meiotic progression.

○Koji Kikuchi1, Toshihiko Fujimori2, Mami Nakagawa2, Keisuke Ohta3, Ryuki Shimada1, Sayoko Fujimura4, Kei-ichiro Yasunaga4, Shingo Usuki4, Naoki Tani4, Akira Nakamura5, Kimi Araki6, Kei-ichiro Ishiguro1 (1. Chromosome Biol., IMEG, Kumamoto Univ., 2. Div. Embryology, NIBB, 3. AIRC, Sch. of Med., Kurume Univ., 4. LILA, IMEG, Kumamoto Univ., 5. Germline Dev. IMEG, Kumamoto Univ., 6. IRDA, Kumamoto Univ.)
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