The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[2PS-02]【J】Eukaryotic translation regulates various biological processes and human diseases

Thu. Dec 4, 2025 2:20 PM - 4:20 PM JST
Thu. Dec 4, 2025 5:20 AM - 7:20 AM UTC
Room 2(Pacifico Yokohama Conference Center 3F, 301)
Organizer: Toshinobu Fujiwara (Kindai University), Akio Yamashita (The University of Ryukyus)
It is widely accepted that translation control plays an important role in a number of different biological processes and diseases. Recent advances in mRNA translation include cap-dependent translation, codon optimality, ribosome collision and translation termination.This workshop will focus on the role of translational control in a variety of areas related to biological processes such as development, integrated stress response, inflammation and neurodegenerative diseases.
2:20 PM - 2:22 PM JST(5:20 AM - 5:22 AM UTC)

Introduction

2:22 PM - 2:35 PM JST(5:22 AM - 5:35 AM UTC)

[2PS-02-01]Applications of a Human Reconstituted Cell-Free Translation System to Structural and Biochemical Analyses

○Takuhiro Ito1, Hiroaki Imataka2 (1. RIKEN, 2. Univ. of Hyogo)
Comment()
2:35 PM - 2:37 PM JST(5:35 AM - 5:37 AM UTC)

Q & A for Each Presentation

2:37 PM - 2:57 PM JST(5:37 AM - 5:57 AM UTC)

[2PS-02-02]Regulatory mechanism of mRNA decay induced by non-optimal codons

○Masanori Yoshinaga1, Fabian Hia1, Yitong Wu1, Sakurako Goto-Ito2, Takuhiro Ito2, Osamu Takeuchi1 (1. Kyoto University, 2. RIKEN)
Comment()
2:57 PM - 3:00 PM JST(5:57 AM - 6:00 AM UTC)

Q & A for Each Presentation

3:00 PM - 3:17 PM JST(6:00 AM - 6:17 AM UTC)

[2PS-02-03]Molecular mechanism of inactive 80S ribosome formation in mammals

○Hirotatsu Imai1, Wakana Iwasaki2, Akira Fukao3, Yukihide Tomari4, Hidehito Kuroyanagi1, Shinichi Nakagawa5, Toshinobu Fujiwara3, Takuhiro Ito2, Akio Yamashita1,3 (1. Univ. Ryukyus, 2. RIKEN, 3. Kindai Univ., 4. Univ. Tokyo, 5. Hokkaido Univ.)
Comment()
3:17 PM - 3:20 PM JST(6:17 AM - 6:20 AM UTC)

Q & A for Each Presentation

3:20 PM - 3:33 PM JST(6:20 AM - 6:33 AM UTC)

[2PS-02-04(2P-188)]Regulation of ribosome collisions and ER-targeted translation by PELO

○Momoko Narita1, Sota Ito1, Satoshi Hashimoto1, Chisato Kikuguchi1, Toru Suzuki1, Toshifumi Inada1 (1. The Institute of Medical Science, The University of Tokyo)
Comment()
3:33 PM - 3:35 PM JST(6:33 AM - 6:35 AM UTC)

Q & A for Each Presentation

3:35 PM - 3:48 PM JST(6:35 AM - 6:48 AM UTC)

[2PS-02-05]Functional Analyses of G3BP1 in miRNA-Mediated Translational Repression

○Ayumi Mori1, Mai Miyao1, Takumi Tomohiro1, Akira Fukao1, Shungo Adachi2, Tohru Natsume3, Koji Onomoto4, Mitsutoshi Yoneyama4, Toru Suzuki5, Tadashi Yamamoto6, Toshinobu Fujiwara1 (1. Kindai University , 2. National Cancer center, 3. AIST, 4. Chiba University, 5. The University of Tokyo, 6. OIST)
Comment()
3:48 PM - 3:50 PM JST(6:48 AM - 6:50 AM UTC)

Q & A for Each Presentation

3:50 PM - 4:03 PM JST(6:50 AM - 7:03 AM UTC)

[2PS-02-06(2P-191)]Investigation of molecular mechanism of ATXN8OS CUG repeat-associated non-AUG translation

○Soyoka Sakamoto1, Hayato Ito1, Mayuka Hasumi1, Makito Hirano2, Yoshitaka Nagai2, Hideki Taguchi3 (1. Institute of Science Tokyo, 2. Kindai University, 3. Science Tokyo)
Comment()
4:03 PM - 4:05 PM JST(7:03 AM - 7:05 AM UTC)

Q & A for Each Presentation

4:05 PM - 4:18 PM JST(7:05 AM - 7:18 AM UTC)

[2PS-02-07(2P-185)]Sperm-specific regulatory mechanism of translation by TCP11

○Taichi Shiraishi1, Chisa Shiraishi1, Kazuya Ichihara1, Sakurako Goto2, Takuhiro Ito2, Koshi Imami3, Akinobu Matsumoto1 (1. Nagoya university, 2. RIKEN, 3. RIKEN.)
Comment()
4:18 PM - 4:20 PM JST(7:18 AM - 7:20 AM UTC)

Q & A for Each Presentation

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