The 48th Annual Meeting of the Molecular Biology Society of Japan
Advanced Search

Session Details

Symposium

[3PS-13]【J】Exploring the fundamental mechanisms of the cardiac system through multidisciplinary research

Fri. Dec 5, 2025 2:20 PM - 4:20 PM JST
Fri. Dec 5, 2025 5:20 AM - 7:20 AM UTC
Room 13(Pacifico Yokohama Conference Center 4F, 418)
Organizer: Saori Tani-Matsuhana (Kobe University), Hajime Fukui (Tokushima University)
Understanding heart development, driven by dynamic cellular interactions among diverse cell types, remains a key challenge. To deepen our knowledge, a multidisciplinary approach to integrate cellular and tissue dynamics supported by both cell and non-cell autonomous principles is essential. This symposium will provide a platform for cross-disciplinary discussions on heart development, showcasing cutting-edge approaches such as spatial transcriptomics, biological imaging, and mathematical modeling.
2:20 PM - 2:21 PM JST(5:20 AM - 5:21 AM UTC)

Introduction

2:21 PM - 2:35 PM JST(5:21 AM - 5:35 AM UTC)

[3PS-13-01]Role of MafB gene in cardiac neural crest development

○Saori Tani-Matsuhana1, Yumi Unozu1, Yuga Kawata1, Kunio Inoue1 (1. Kobe University)
Comment()
2:35 PM - 2:38 PM JST(5:35 AM - 5:38 AM UTC)

Q & A for Each Presentation

2:38 PM - 2:52 PM JST(5:38 AM - 5:52 AM UTC)

[3PS-13-02]Topographical gene switch in the cardiopharyngeal neural crest cell diversity and its progression to calcification lesions

○Akiyasu Iwase1,2, Yasunobu Uchijima1, Daiki Seya1, Mayuko Kida1, Hiroki Higashiyama1, Kazuhiro Matsui1, Akashi Taguchi2, Yukihiro Harada3, Yunce Wang3, Shogo Yamamoto4, Shiro Fukuda4, Seitaro Nomura5, Takahide Kohro6, Chisa Shukunami7, Haruhiko Akiyama8, Masahide Seki9, Akinori Kanai9, Yutaka Suzuki9, Teruhisa Kawamura3, Osamu Nakagawa3,12, Hiroto Katoh11,10, Shumpei Ishikawa11,10, Youichiro Wada2, Hiroyuki Aburatani4, Yukiko Kurihara1,13, Sachiko Miyagawa-Tomita1,14, Hiroki Kurihara1,2,15 (1. Dept. of Phys. chem. and Metab., Grad. Sch. of Med., Univ. of Tokyo, 2. ISC, Univ. of Tokyo, 3. Dept. of Biomed. Sci., Col. of Life Sci., Ritsumeikan Univ., 4. Genome Sci. Div., RCAST, Univ. of Tokyo, 5. Dept. of Card. Med., Grad. Sch. of Med., Univ. of Tokyo, 6. Dept. of Clin. Info., Jichi Med Univ, 7. Dept. of Mol. Bio. and Biochem., Grad. Sch. of Biomed. and Health Sci. Hiroshima Univ, 8. Dept. of Orthop. Surg., Gifu Univ., 9. Dept. of. Med. Genome. Sci., Grad. Sch. of Front Sci., Univ. of Tokyo, 10. Dept. of Prev. Med., Grad. Sch. of Med., Univ. of Tokyo, 11. Dept. of Path. NCC-EPOC, 12. Dept. of Genom. Med., Res. Inst., NCVC, 13. Kagawa Nurt. Univ., 14. Dept. of Animal Health Tech., Yamazaki Univ. Animal Health Tech, 15. IRCMS, Kumamoto Univ.)
Comment()
2:52 PM - 2:55 PM JST(5:52 AM - 5:55 AM UTC)

Q & A for Each Presentation

2:55 PM - 3:03 PM JST(5:55 AM - 6:03 AM UTC)

[3PS-13-03(3P-598)]Derivation of human post-mitotic cardiomyocyte from tetraploid induced pluripotent stem cells

○Ittetsu Nakajima1,2, Shimane Mitsuyoshi3, Grace Holmstrom4, Yuichiro Miyaoka1,2,5 (1. Tokyo Metropolitan Institute of Medical Sciece, 2. Institute of Science Tokyo, 3. Nanion Technologies Japan K.K., 4. Pitzer College, 5. Ochanomizu University)
Comment()
3:03 PM - 3:06 PM JST(6:03 AM - 6:06 AM UTC)

Q & A for Each Presentation

3:06 PM - 3:14 PM JST(6:06 AM - 6:14 AM UTC)

[3PS-13-04(3P-542)]Human zebrafish chimeric heart

Jo Onozuka1, Issa Watanabe1, Riko Taira1, Shin Kadota2, Hajime Ichimura2, Yuji Shiba2, Chinmoy Patra3, ○Kiyoshi Ohnuma1 (1. Nagaoka University of Technology, 2. Shinshu University, 3. Agharkar Research Institute)
Comment()
3:14 PM - 3:17 PM JST(6:14 AM - 6:17 AM UTC)

Q & A for Each Presentation

3:17 PM - 3:31 PM JST(6:17 AM - 6:31 AM UTC)

[3PS-13-05]Endothelial-zippering proceeds by sensing heartbeat-driven force through Cadherin-6 during heart-vessel connection in zebrafish

○Moe Fukumoto1, Haruko Takano2, Hajime Fukui3, Ayano Chiba4, Keisuke Sako5, Hiroyuki Nakajima1, Naoki Mochizuki1 (1. National Cerebral and Cardiovascular Research Center Research Institute, 2. Nippon Medical School, 3. Tokushima University, 4. Yamagata Univiesity, 5. Keio University)
Comment()
3:31 PM - 3:34 PM JST(6:31 AM - 6:34 AM UTC)

Q & A for Each Presentation

3:34 PM - 3:48 PM JST(6:34 AM - 6:48 AM UTC)

[3PS-13-06]Embryological cellular origins and hypoxia-mediatedmechanisms in PIK3CA-driven refractory vascularmalformations

○Kazuaki Maruyama1, Souta Torii1, Kyouko Imanaka-Yoshida1,2 (1. Mie University, Dept of Pathology and Matrix Biology, 2. Mie University, cardiology)
Comment()
3:48 PM - 3:51 PM JST(6:48 AM - 6:51 AM UTC)

Q & A for Each Presentation

3:51 PM - 3:59 PM JST(6:51 AM - 6:59 AM UTC)

[3PS-13-07(3P-227)]Conversion of mitochondrial inner structure during heart development

○Yuto Ishikawa1, Shun Hirose1, Misaki Emori1, Isshin Shiiba1, Shigeru Yanagi1 (1. Gakushuin University)
Comment()
3:59 PM - 4:02 PM JST(6:59 AM - 7:02 AM UTC)

Q & A for Each Presentation

4:02 PM - 4:16 PM JST(7:02 AM - 7:16 AM UTC)

[3PS-13-08]The role of chiral nematic pattern in cardiac fiber structure in mammalian heart

○Naofumi Kawahira1,2,3, Takaki Yamamoto4, Takumi Washio5, Kenta Yashiro6, Kyogo Kawaguchi4, Atsushi Nakano1,3 (1. UCLA, 2. RIKEN , 3. Jikei Univ., 4. Univ. of Tokyo, 5. UTHeart, 6. KPUM)
Comment()
4:16 PM - 4:19 PM JST(7:16 AM - 7:19 AM UTC)

Q & A for Each Presentation

4:19 PM - 4:20 PM JST(7:19 AM - 7:20 AM UTC)

Conclusion

Back to Category List