The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[3PS-15]【J】Molecules in Mitochondria -Rethinking of their functions from basics-

Fri. Dec 5, 2025 2:20 PM - 4:20 PM JST
Fri. Dec 5, 2025 5:20 AM - 7:20 AM UTC
Room 15(Pacifico Yokohama Conference Center 5F, 501)
Organizer: Yuhei Araiso (Kanazawa University), Saori Yoshii (The University of Tokyo)
Mitochondria are essential organelles that act as centers of cellular homeostasis. In recent years, mitochondrial research has made remarkable progress as their novel functions have been revealed one after another. Here, we introduce the latest findings about mitochondrial basic biology mainly by young researchers. By discussing functions, structures and regulatory techniques of the molecules working in mitochondria, we aim to explore the roots of mitochondrial biology and a new vision of mitochondria.
2:20 PM - 2:21 PM JST(5:20 AM - 5:21 AM UTC)

Introduction

2:21 PM - 2:38 PM JST(5:21 AM - 5:38 AM UTC)

[3PS-15-01]Structure and dynamics of the translocase of the outer mitochondrial membrane

○Yuhei Araiso1, Nanako Kobayashi1 (1. Div. Health Sci., Kanazawa Univ.)
Comment()
2:38 PM - 2:56 PM JST(5:38 AM - 5:56 AM UTC)

[3PS-15-02]What are the minimal essential elements defining mitochondrial targeting proteins?

○Yamato Yoshida1 (1. The Univ. of Tokyo)
Comment()
2:56 PM - 3:14 PM JST(5:56 AM - 6:14 AM UTC)

[3PS-15-03]Mitochondrial ribotoxic stress triggers retrograde signaling for proteostasis maintenance

○Taisei Wakigawa1, Sylvia Almeida3, Yushin Ando4, Isshin Shiiba5, Koki Nakamura6, Mari Mito1, Masami Shima1, Margo Le Creff-Le Balc’h1, Hajime Komaki6, Hijiri Oshio5, Yuichi Shichino1, Shigeru Yanagi5, Osamu Nureki4, Yusuke Hirabayashi6, Yuzuru Itoh4, Charles Boone3, Shintaro Iwasaki1,2 (1. RIKEN, Pioneering Research Institute, 2. Graduate School of Frontier Sciences, The University of Tokyo, 3. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 4. Graduate School of Science, The University of Tokyo, 5. Faculty of Science, Gakushuin University, 6. Graduate School of Engineering, The University of Tokyo)
Comment()
3:14 PM - 3:26 PM JST(6:14 AM - 6:26 AM UTC)

[3PS-15-04(3P-900)]Taurine-Induced tRNA Stabilization Restores Mitochondrial Function in KARS1-Mutant iPS Cells

○Takeshi Tokuyama1, Haruna Tani2, Taisei Wakigawa3, Kumiko Iwabuchi4, Fuad Gandhi Torizal1, Razan E Ahmed1, Pamorn Chittavanich1, Kouki Mii1, Eri Kitaguti1, Wei Fan-Yan2,1, Iwasaki Shintaro 3, Hideki Uosaki1 (1. Div. Funct. Biochem., Dept. Biochem., Jichi Med. Univ., Sch. Med., 2. Dept. of Modomics Biol. & Med., IDAC, Tohoku Univ., 3. RNA Sys. Biochem. Lab., RIKEN CPR, 4. Div. of Regen. Med., Ctr. for Mol. Med., Jichi Med. Univ.)
Comment()
3:26 PM - 3:44 PM JST(6:26 AM - 6:44 AM UTC)

[3PS-15-05]Targeted protein degradation in mitochondria

○Shusuke Tomoshige1 (1. Grad. Sch. Life Sci. Tohoku Univ.)
Comment()
3:44 PM - 4:02 PM JST(6:44 AM - 7:02 AM UTC)

[3PS-15-06(3P-405)]A Novel Role of Organelle Contact Sites in the Regulation of Mitochondrial Iron Dynamics

○Hijiri Oshio1, Isshin Shiiba1, Shigeru Yanagi1 (1. Gakushuin university)
Comment()
4:02 PM - 4:19 PM JST(7:02 AM - 7:19 AM UTC)

[3PS-15-07]Mitochondrial diffusion barrier during asymmetric cell division in yeast

○Saori R. Yoshii1,2, Yves Barral2 (1. The University of Tokyo, 2. ETH Zurich)
Comment()
4:19 PM - 4:20 PM JST(7:19 AM - 7:20 AM UTC)

Conclusion

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