The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[3AS-16]【J】Bidirectional molecular network in fetal-maternal crosstalk regulating fetal development

Fri. Dec 5, 2025 9:00 AM - 11:00 AM JST
Fri. Dec 5, 2025 12:00 AM - 2:00 AM UTC
Room 16(Pacifico Yokohama Conference Center 5F, 502)
Organizer: Kenichi Miharada (Kumamoto University), Fumiko Toyoshima (Institute of Science Tokyo)
Mammalian development is highly dependent on molecular interactions between the mother and the fetus, in addition to the fetus-autonomous mechanisms. Recent analyses of the feto-maternal crosstalk at the genetic, molecular, and cellular levels have revealed that the maternal environment during early development is deeply involved in the health of the offspring after birth through epigenomic regulation. In this symposium, we will discuss the molecular mechanisms of the bidirectional network involved in feto-maternal crosstalk.
9:00 AM - 9:01 AM JST(12:00 AM - 12:01 AM UTC)

Introduction

9:01 AM - 9:15 AM JST(12:01 AM - 12:15 AM UTC)

[3AS-16-01]Prostaglandin receptor signaling mediates the first maternal-fetal interaction, implantation.

○Yukihiko Sugimoto1 (1. Kumamoto Univ.)
Comment()
9:15 AM - 9:18 AM JST(12:15 AM - 12:18 AM UTC)

Q & A for Each Presentation

9:18 AM - 9:32 AM JST(12:18 AM - 12:32 AM UTC)

[3AS-16-02]Bioactive lipids-mediating feto-maternal interactions

○Shizu Aikawa1 (1. The University of Tokyo)
Comment()
9:32 AM - 9:35 AM JST(12:32 AM - 12:35 AM UTC)

Q & A for Each Presentation

9:35 AM - 9:49 AM JST(12:35 AM - 12:49 AM UTC)

[3AS-16-03]Neural Circuit Remodeling Underlying Enhanced Feeding During Pregnancy in Mice

○Kazunari Miyamichi Miyamichi1 (1. RIKEN)
Comment()
9:49 AM - 9:52 AM JST(12:49 AM - 12:52 AM UTC)

Q & A for Each Presentation

9:52 AM - 10:06 AM JST(12:52 AM - 1:06 AM UTC)

[3AS-16-04]The impact of maternal DHA-containing phospholipid syntesis for maternal-to-fetal DHA transfer and neuropsychiatric development

○Keisuke Yanagida1 (1. The Jikei University School of Medicine)
Comment()
10:06 AM - 10:09 AM JST(1:06 AM - 1:09 AM UTC)

Q & A for Each Presentation

10:09 AM - 10:23 AM JST(1:09 AM - 1:23 AM UTC)

[3AS-16-05]Maternal organ remodelling and maternal-fetal interactions during pregnancy and lactation

○Tomotsune Ameku1, Fumiko Toyoshima1 (1. Science Tokyo)
Comment()
10:23 AM - 10:26 AM JST(1:23 AM - 1:26 AM UTC)

Q & A for Each Presentation

10:26 AM - 10:38 AM JST(1:26 AM - 1:38 AM UTC)

[3AS-16-06]Placenta-derived signaling molecules and maternal-fetal interaction

○Joji Kusuyama1 (1. Institute of Science Tokyo)
Comment()
10:38 AM - 10:41 AM JST(1:38 AM - 1:41 AM UTC)

Q & A for Each Presentation

10:41 AM - 10:55 AM JST(1:41 AM - 1:55 AM UTC)

[3AS-16-07(3P-159)]Single-nucleus RNA-seq Analysis of First-trimester Human Placentas to Elucidate Early Pathogenesis of Preeclampsia

○Akihito Sagara1,2, Tomoaki Koga1, Munekage Yamaguchi2, Osamu Shimokawa3, Hiroyasu Ohashi3, Ritsuko Pooh4, Eiji Kondoh2, Mitsuyoshi Nakao1 (1. Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, 2. Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, 3. CRIFM Prenatal Medical Clinic, 4. Department of Clinical Genetic Research, Ritz Medical Co., Ltd)
Comment()
10:55 AM - 10:58 AM JST(1:55 AM - 1:58 AM UTC)

Q & A for Each Presentation

10:58 AM - 11:00 AM JST(1:58 AM - 2:00 AM UTC)

Conclusion

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