The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Mini-Symposia

[3MS-16]【E】Fascinating Skeletal Muscle Biology: A New Journey Towards Healthy Longevity

Fri. Dec 5, 2025 11:15 AM - 12:35 PM JST
Fri. Dec 5, 2025 2:15 AM - 3:35 AM UTC
Room 16(Pacifico Yokohama Conference Center 5F, 502)
Organizer: Naoki Suzuki (Tohoku University), Yoshitsugu Aoki (National Center of Neurology and Psychiatry)
Skeletal muscle is the largest organ in the human body, playing a central role in maintaining daily physical activity and health. Muscle dysfunction is deeply involved not only in muscle diseases but also in sarcopenia. Understanding skeletal muscle is essential for extending healthy life expectancy in our aged society. This symposium aims to open new horizons in skeletal muscle biology by comprehensively understanding, at the molecular level, the abnormal protein aggregation and breakdown of tissue homeostasis mechanisms in muscle diseases and sarcopenia.
11:15 AM - 11:16 AM JST(2:15 AM - 2:16 AM UTC)

Introduction

11:16 AM - 11:29 AM JST(2:16 AM - 2:29 AM UTC)

[3MS-16-01]The nuclear pore pathology in hereditary inclusion body myopathy

○Kensuke Ikeda1, Rumiko Izumi1, Naoki Suzuki1, Hitoshi Warita1, Masashi Aoki1 (1. Tohoku University)
Comment()
11:29 AM - 11:43 AM JST(2:29 AM - 2:43 AM UTC)

[3MS-16-02]The role of ZNF683 and XCL1 in tissue resident memory T cells in pathomechanism of Inclusion Body Myositis

○Francia Victoria Abarcar De Los Reyes1, Shinichiro Hayashi1, Satoru Noguchi1, Ichizo Nishino1 (1. National Center of Neurology and Psychiatry)
Comment()
11:43 AM - 12:00 PM JST(2:43 AM - 3:00 AM UTC)

[3MS-16-03]Loss of TDP-43 Splicing Repression Occurs in Myonuclei of Inclusion Body Myositis Patients

○Chiseko Ikenaga1,2, Andrew B. Wilson2, Katherine E. Irwin3, Aswathy Peethambaran Mallika3, Collin Kilgore2, Irika R. Sinha3, Elizabeth H. Michelle2, Jonathan P. Ling3, Philip C. Wong3, Thomas E. Lloyd2,4 (1. Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, 2. Department of Neurology, Johns Hopkins University School of Medicine, 3. Department of Pathology, Johns Hopkins University School of Medicine, 4. Department of Neurology, Baylor College of Medicine)
Comment()
12:00 PM - 12:16 PM JST(3:00 AM - 3:16 AM UTC)

[3MS-16-04]Attenuation of Skeletal Muscle Aging Through Enhanced Mitochondrial Function

○Tomoko Kasahara1 (1. Graduate School of Medicine, Tohoku University)
Comment()
12:16 PM - 12:34 PM JST(3:16 AM - 3:34 AM UTC)

[3MS-16-05]Non-regenerative myogenesis

○So-ichiro Fukada1 (1. The University of Osaka)
Comment()
12:34 PM - 12:35 PM JST(3:34 AM - 3:35 AM UTC)

Conclusion

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