The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[3AS-04]【J】Autophagy expanded: decoding membrane interface biology

Fri. Dec 5, 2025 9:00 AM - 11:00 AM JST
Fri. Dec 5, 2025 12:00 AM - 2:00 AM UTC
Room 4(Pacifico Yokohama Conference Center 3F, 303)
Organizer: Nobuo Noda (Hokkaido University), Junichi Ikenouchi (Kyushu University)
Phase separation research has highlighted the functions of protein assemblies, but their collaboration with lipid assemblies has received less attention. In autophagy, protein assemblies dynamically interact with lipid assemblies at membrane interfaces, driving complex membrane dynamics. In this symposium, we will introduce the latest findings on how this “membrane interface molecular concerto" contributes to autophagy as well as wide range of biological phenomena.
9:00 AM - 9:18 AM JST(12:00 AM - 12:18 AM UTC)

[3AS-04-01]Analysis of membrane interface phenomena driving autophagosome biogenesis

○Nobuo N. Noda1,2 (1. Hokkaido University, 2. Institute of Microbial Chemistry)
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9:18 AM - 9:36 AM JST(12:18 AM - 12:36 AM UTC)

[3AS-04-02]Molecular dynamics simulation for lipid transfer mechanism in autophagosome formation

○Yuji Sakai1 (1. Yokohama City University)
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9:36 AM - 9:51 AM JST(12:36 AM - 12:51 AM UTC)

[3AS-04-03(3P-230)]ESCRT-III-mediated lysosomal micronucleophagy mitigates the STING inflammatory signaling

○Asuka Kodaira1, Fuma Sunayama1, Shiori Hamano1, Yoshihiko Kuchitsu1, Tomohiko Taguchi1 (1. Graduate School of Life Sciences, Tohoku University)
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9:51 AM - 10:06 AM JST(12:51 AM - 1:06 AM UTC)

[3AS-04-04(3P-228)]The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders

○Ryohei Sakai1,2, Shu Aizawa2, Hyeon-Cheol Lee-Okada3, Chihana Kabuta2, Tatsuo Mano2, Tadafumi Hashimoto2, Ikuko Koyama-Honda4, Tomohiro Kabuta2 (1. Nippon Medical School, 2. National Center of Neurology and Psychiatry, 3. Juntendo University Graduate School of Medicine, 4. The University of Tokyo)
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10:06 AM - 10:24 AM JST(1:06 AM - 1:24 AM UTC)

[3AS-04-05]Molecular Mechanisms of Ebola Virus Particle Formation from the Perspective of Membrane Interface Biology

○Asuka Nanbo1,2, Kento Yamada1, Wakako Furuyama1 (1. CCPID・Nagasaki Univ., 2. NEKKEN・Nagasaki Univ.)
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10:24 AM - 10:42 AM JST(1:24 AM - 1:42 AM UTC)

[3AS-04-06]Nanoscale understanding of synaptic organization and disorders

○Yuko Fukata1 (1. Nagoya University Graduate School of Medicine)
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10:42 AM - 11:00 AM JST(1:42 AM - 2:00 AM UTC)

[3AS-04-07]Dissecting the Molecular Mechanism of Bleb Formation

○Junichi Ikenouchi Ikenouchi1 (1. Kyushu Univ.)
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