Session Details

[3PS-06]【E】Understanding the Diverse Functions and Pathophysiology of the Kidney and Blood Pressure Through Cutting-Edge Research

Fri. Dec 5, 2025 2:20 PM - 4:20 PM JST
Fri. Dec 5, 2025 5:20 AM - 7:20 AM UTC
Room 6(Pacifico Yokohama Conference Center 3F, 311+312)
Organizer: Takafumi Toyohara (Tohoku University Hospital), Kengo Azushima (Yokohama City University)
The kidney has the highest blood flow per unit weight in the body and serves vital roles beyond waste excretion, including blood pressure regulation and endocrine function. The pathophysiology of kidney diseases is complex, involving fluid dynamics, hypertension, and inflammation. Advances in single-cell omics and patient-derived iPS cells have clarified renal regeneration, and novel researches of mechanobiology and humoral regulation have advanced the understanding of hypertension. This symposium will share the latest findings and therapeutic prospects.

[3PS-06-01]Understanding mechanisms of kidney inflammation through cancer therapy- immune checkpoint blockade associated acute kidney injury

○Naoka Murakami1 (1. Washington University in St. Louis)
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[3PS-06-02(3P-960)]The Pathophysiological Role of Skin Tissue Renin-Angiotensin System in Hypertension

○Shinya Taguchi1 (1. Yokohama City University)
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[3PS-06-03]Towards precision therapies: unravelling mechanisms of non-HLA genetic variants associated with allograft kidney disease progression.

○Madhav C Menon1 (1. Yale University school of Medicine)
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[3PS-06-04]Establishing immune-competent organoids to unravel immune modulation in kidney development and disease

○Yun Xia1 (1. Nanyang Technological University Singapore)
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[3PS-06-05]Exercise-mimicking mechanical stimulation to the head ameliorates hypertension

○Naoyoshi Sakitani1, Yasuhiro Sawada2 (1. National Institute of Advanced Industrial Science and Technology, 2. National Rehabilitation Center for Persons with Disabilities)
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[3PS-06-06(3P-656)]Development of novel cell therapies for AKI and CKD using human iPS cell-derived nephron progenitor cells

○Toshikazu Araoka1 (1. Center for iPS cell research and application, Kyoto university)
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