The 48th Annual Meeting of the Molecular Biology Society of Japan
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Session Details

Symposium

[3AS-07]【E】Chromosome structure and function driven by supramolecular complexes

Fri. Dec 5, 2025 9:00 AM - 11:00 AM JST
Fri. Dec 5, 2025 12:00 AM - 2:00 AM UTC
Room 7(Pacifico Yokohama Conference Center 3F, 313+314)
Organizer: Yasuto Murayama (National Institute of Genetics), Motoko Takahashi (Cancer Institute of the Japanese Foundation for Cancer Research)
Various protein complexes weave genomic DNA into chromosomes to regulate a variety of biological activities, including transcription, replication and chromosome segregation. While our molecular understanding of each factor has been accumulating for years, it has been emerged that these protein complexes exert physiological functions by forming supramolecular complexes through higher order interactions. In this symposium, we will discuss the supramolecular complexes underlying chromosome functions with researchers working in a wide range of chromosome fields.
9:00 AM - 9:01 AM JST(12:00 AM - 12:01 AM UTC)

Introduction

9:01 AM - 9:13 AM JST(12:01 AM - 12:13 AM UTC)

[3AS-07-01]The biochemical reconstitution and molecular basis of sister chromatid cohesion

○Yasuto Murayama1, Yumiko Kurokawa1 (1. National Institute of Genetics)
Comment()
9:13 AM - 9:17 AM JST(12:13 AM - 12:17 AM UTC)

Q & A for Each Presentation

9:17 AM - 9:29 AM JST(12:17 AM - 12:29 AM UTC)

[3AS-07-02]Dynamic clustering of KIF4A promotes mitotic chromosome organization

○Motoko Takahashi1, Chang Liu1, Toru Hirota1 (1. Div. Exp. Pathol., Cancer Inst., JFCR)
Comment()
9:29 AM - 9:33 AM JST(12:29 AM - 12:33 AM UTC)

Q & A for Each Presentation

9:33 AM - 9:45 AM JST(12:33 AM - 12:45 AM UTC)

[3AS-07-03(3P-375)]Oncoproteins as "accelerants": how cancer transcription factors can disrupt higher-order interactions to accelerate target diffusion and stimulate activity

Andrej Paluda1, ○Donald Cameron1 (1. Institute for Quantitative Biosciences, University of Tokyo)
Comment()
9:45 AM - 9:49 AM JST(12:45 AM - 12:49 AM UTC)

Q & A for Each Presentation

9:49 AM - 10:01 AM JST(12:49 AM - 1:01 AM UTC)

[3AS-07-04(3P-437)]A genome-wide screen reveals novel regulators of centriole-independent spindle assembly

○Muhammad Hamzah1, Midori Ohta1, Franz Meitinger1 (1. Okinawa Institute of Science and Technology)
Comment()
10:01 AM - 10:05 AM JST(1:01 AM - 1:05 AM UTC)

Q & A for Each Presentation

10:05 AM - 10:20 AM JST(1:05 AM - 1:20 AM UTC)

[3AS-07-05]Molecular mechanism of chromatin compartmentalization in Sulfolobus.

○Je-Kyung Ryu1 (1. Seoul National University)
Comment()
10:20 AM - 10:24 AM JST(1:20 AM - 1:24 AM UTC)

Q & A for Each Presentation

10:24 AM - 10:39 AM JST(1:24 AM - 1:39 AM UTC)

[3AS-07-06]Structural and functional analysis of transcription complexes driving genome architecture dynamics

○Kayo Nozawa1 (1. Institute of Science Tokyo)
Comment()
10:39 AM - 10:43 AM JST(1:39 AM - 1:43 AM UTC)

Q & A for Each Presentation

10:43 AM - 10:55 AM JST(1:43 AM - 1:55 AM UTC)

[3AS-07-07]Kinetochore maintenance during the cell-cycle progression in vertebrate cells

○Tatsuo Fukagawa1 (1. The University of Osaka)
Comment()
10:55 AM - 10:59 AM JST(1:55 AM - 1:59 AM UTC)

Q & A for Each Presentation

10:59 AM - 11:00 AM JST(1:59 AM - 2:00 AM UTC)

Conclusion

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