Session Details
[3AS-09]【J】Multi-level understanding and functional regulation of neurotransmitter receptors: From atoms to living organisms
Fri. Dec 5, 2025 9:00 AM - 11:00 AM JST
Fri. Dec 5, 2025 12:00 AM - 2:00 AM UTC
Fri. Dec 5, 2025 12:00 AM - 2:00 AM UTC
Room 9(Pacifico Yokohama Conference Center 4F, 411+412)
Organizer: Shigeki Kiyonaka (Nagoya University), Atsuko Yamashita (The University of Osaka)
Advances in cryo-EM and AI-based structure prediction have advanced our understanding of neurotransmitter receptors at the atomic level. In addition, progress has been made in dynamic analysis, such as high-speed AFM, to complement such static structures. In addition, functional regulation methods including chemical biology have also advanced. In this symposium, we will discuss such current situations and their perspectives.
[3AS-09-01]Structure and function of amino acid-sensing taste receptors
○Atsuko Yamashita1 (1. The University of Osaka)
[3AS-09-02]Molecular basis of cooperative activation of voltage-gated sodium channels.
○Ayumi Sumino1 (1. Graduate School of Biostudies, Kyoto University)
[3AS-09-03]Structural insights into functions of NMDA receptors in basic neurobiology and neuroimmunology
○Hiro Furukawa Furukawa1 (1. Cold Spring Harbor Laboratory)
[3AS-09-04]Structural insights into the allosteric inhibition of P2X receptors for drug discovery
○Motoyuki Hattori1 (1. Fudan University)
[3AS-09-05(3P-702)]A GPCR conserved from human to nematode functions as thermo-receptor and is involved in heat acclimation of C. elegans
○Hiromu Ueka1,2,3, Chinatsu Morimoto1,2,3, Chie Miyazaki2, Kohei Ohnishi1,2,3, Tohru Miura1,2,3, Ohta Akane1,2,3, Atsushi Kuhara1,2,3,4 (1. Graduate school of Natural Science, Konan Univ., 2. Faculty of Science and Engineering, Konan Univ., 3. nstitute for Integrative Neurobiology, Konan Univ., 4. AMED-PRIME)
[3AS-09-06]A novel chemogenetic strategy for controlling target GPCRs in a cell-type-specific manner in living animals
○Shigeki Kiyonaka1 (1. Nagoya Univ.)
