Presentation Information
[1P-139]Presenilin is essential for ApoE secretion, a novel role of presenilin involved in Alzheimer's disease pathogenesis
*Kun Zou1, Sadequl Islam1, Yang Sun1, Yuan Gao1, Tomohisa Nakamura1, Noriyuki Kimura2, Etsuro Matsubara2, Kensaku Kasuga3, Takeshi Ikeuchi3, Taisuke Tomita4, Makoto Michikawa1 (1. Dept Biochem, Grad Sch Med, Nagoya City Univ, Nagoya, Japan, 2. Dept Neurol, Sch Med, Oita Univ, Oita, Japan, 3. Dept Mol Genet, Brain Res Inst, Niigata Univ, Niigata, Japan, 4. Dept Neuropathol Neurosci, Faculty Pharm Sci, Univ of Tokyo, Tokyo, Japan)
Keywords:
Alzheimer's disease,Presenilin,ApoE,Secretion
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