Presentation Information
[1P-146]Insulin deficiency increases Sirt2 level in streptozotocin-treated Alzheimer's disease model mice: Sirt2 increases tau phosphorylation through ERK activation
*Chunyu Zhou1, Cha-Gyun Jung1, Mi-Jeong Kim2, Atsushi Watanabe3, Mona Abdelhamid1, Ferdous Taslima1, Makoto Michikawa1 (1. Department of Biochemistry, Nagoya City University Graduate School of Medical Sciences, 2. Department of Food & Biotechnology, Korea University, 3. Laboratory of Research Advancement, Research Institute, National Center for Geriatrics and Gerontology)
Keywords:
Alzheimer’s disease,Sirt2,tau
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