Session Details
[Pe-008]English Poster Session 008 Motor neuron disease (ALS：Molecular pathogenetic mechanism 1)
Wed. May 21, 2025 5:20 PM - 6:40 PM JST
Wed. May 21, 2025 8:20 AM - 9:40 AM UTC
Wed. May 21, 2025 8:20 AM - 9:40 AM UTC
ポスター会場(大阪国際会議場3F イベントホール)
Chairs: Yohei Iguchi（Neurology, Nagoya Univ., Japan）, Taro Ishiguro（Science Tokyo, Dept of Neurology and Neurological science, Japan）
[Pe-008-1]Altered FUS expression and synaptic function in ALS-FUS patients-derived iPSC motor neurons
Satoshi Yokoi1,2, Ryo Chikuchi2, Yuta Kato1, Yohei Iguchi2, Ryoichi Nakamura3, Genki Tohnai4, Naoki Atsuta3, Yohei Okada5, Gen Sobue6, Masahisa Katsuno2 (1.Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Japan, 2.Department of Neurology, Nagoya University Graduate School of Medicine, Japan, 3.Department of Neurology, Aichi Medical University, Japan, 4.Division of ALS Research, Aichi Medical University School of Medicine, Japan, 5.Division of Neural iPSC Research Institute for Medical Science of Aging, Aichi Medical University, Japan, 6.Aichi Medical University, Japan)
[Pe-008-2]Conditional Erbb4 knockout mice demonstrated nuclear TDP-43 reduction and motor neuron degeneration
Chihiro Matsumoto1, Tomohiro Kabuta1, Keiji Wada1, Tadafumi Hashimoto1, Yuji Takahashi2 (1.Department of Degenerative Neurological Diseases, National Center Hospital, National Center of Neurology and Psychiatry, Japan, 2.Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Japan)
[Pe-008-3]Loss of TDP-43 function results in a decrease in NEAT1, which exacerbates motor neuron degeneration
Yu Kawakami1, Yohei Iguchi1, Ryo Chikuchi1, Takashi Yoshimura1, Yoshinobu Amakusa1, Satoshi Yokoi1, Yuichi Riku2, Yasushi Iwasaki2, Tetsuro Hirose3, Shinichi Nakagawa4, Masahisa Katsuno1 (1.Nagoya University Graduate School of Medicine, Neurology, Japan, 2.Institute for Medical Science of Aging, Aichi Medical University, Japan, 3.Graduate School of Frontier Biosciences, Osaka University, Japan, 4.Faculty of Pharmaceutical Sciences, Hokkaido University, Japan)
[Pe-008-4]Differential characteristics of pathological progression of TDP-43 variants in mouse ALS/FTLD model
Hideki Mori1, Shintaro Tsuboguchi1, Tokiharu Sato2, Yuka Nakamura2, Taisuke Kato3, Akihiro Sugai1, Osamu Onodera1,3, Masaki Ueno2 (1.Department of Neurology, Brain Research Institute, Niigata University, Japan, 2.Department of System Pathology for Neurological Disorders, Brain Research Institute, Niigata University, Japan, 3.Department of Molecular Neuroscience, Brain Research Institute, Niigata University, Japan)
[Pe-008-5]Proteomics-Driven Connectomics Identifies Early Synaptic Biomarkers in Amyotrophic Lateral Sclerosis
Rifaldy Fajar1, Prihantini Prihantini2, Andi Nursanti3, Asfirani Umar4, Sahnaz V. Putri5 (1.Department of Mathematics and Computer Science, Karlstad University, Sweden, 2.Machine Learning for BioMedicine Laboratory, Bandung Institute of Technology, Indonesia, 3.Department of Pharmacy, Andini Persada College of Health Sciences, Indonesia, 4.Neurology Research Unit, BLK General Hospital, Indonesia, 5.Health Management Laboratory, International University Semen Indonesia, Indonesia)