[3P] Poster

[C. Sensory and Perceptual Systems] Somatosensation

[3P-077] μ-opioid receptor activation in the medial prefrontal cortex plays crucial roles in placebo analgesia

*Hiroyuki Neyama^1,2, Yuping Wu¹, Yuka Nakaya³, Shigeki Kato⁴, Tomoko Shimizu¹, Tsuyoshi Tahara¹, Mika Shigeta¹, Michiko Inoue¹, Kazunari Miyamichi⁵, Natsuki Matsushita⁶, Tomoji Mashimo⁷, Yoshiki Miyasaka⁸, Yi Dai⁹, Koichi Noguchi⁹, Yasuyoshi Watanabe¹⁰, Masayuki Kobayashi³, Kazuto Kobayashi⁴, Yilong Cui^1,11 (1. Laboratory for Biofunction Dynamics Imaging, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan, 2. Multiomics Platform, CCII, Graduate School of Medicine, Kyoto University, 3. Department of Pharmacology, Nihon University School of Dentistry, Tokyo, Japan, 4. Department of Molecular Genetics, Fukushima Medical University Institute of Biomedical Sciences, Fukushima, Japan, 5. Laboratory for Comparative Connections, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan, 6. Division of Laboratory Animal Research, Aichi Medical University School of Medicine, Aichi, Japan, 7. Division of Animal Genetics, Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 8. Laboratory of Reproductive Engineering, Institute of Experimental Animal Sciences, Osaka University Medical School, Osaka, Japan, 9. Department of Anatomy and Neuroscience, Hyogo Medical University, Hyogo, Japan, 10. Laboratory for Pathophysiological and Health Science, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan, 11. Laboratory for Brain-Gut Homeostasis, Hyogo Medical University, Hyogo, Japan)

Keywords:

Placebo analgesia,Opioid receptor,Descending pain inhibitory pathway,Neuropathic pain

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