[3P] Poster

[H. Disorders of Nervous Systems] Schizophrenia

[3P-259] Aberrant brain function and social deficits in a novel DISC1 knockout macaque model: a multidimensional MRI and behavioral study

*Ziguo Lan^1,2,7, Tomoyuki Tsukiyama^1,5, Keigo Hikishima³, Chih-Yang Chen¹, Yuta Shinto¹, Naoya Oishi⁴, Shin-ichi Urayama⁴, Tomohisa Okada⁸, Masataka Nakaya^1,5, Chizuru Iwatani⁵, Hideaki Tsuchiya⁵, Koko Ishizuka⁶, Akira Sawa^6,7, Hirotaka Onoe^4,9, Tadashi Isa^1,2,4 (1. Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan, 2. Department of Neuroscience, Kyoto University Graduate School of Medicine, Kyoto, Japan, 3. Medical Devices Research Group, Health and Medical Research Institute, AIST, Tsukuba, Japan, 4. Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan, 5. Research Center for Animal Life Science, Shiga University of Medical Science, Otsu, Japan, 6. The Schizophrenia Center, Johns Hopkins University School of Medicine, Baltimore, USA, 7. Department of Frontier and International Psychiatry, Kyoto University Graduate School of Medicine, Kyoto, Japan, 8. Support Unit for Functional Magnetic Resonance Imaging, Research Resources Division, RIKEN-CBS, Wako, Japan, 9. The Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan)

Keywords:

DISC1,Non-human primate,Brain imaging,Psychotic-like endophenotype

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