Session Details
[S06]Chemical Biology for Pharmaceutical Sciences (Frontier of life science research by innovative chemical tools)
Thu. Mar 26, 2020 9:00 AM - 11:00 AM JST
Thu. Mar 26, 2020 12:00 AM - 2:00 AM UTC
Thu. Mar 26, 2020 12:00 AM - 2:00 AM UTC
[Room T] Sakura 1F
Organizers: Mako Kamiya (Grad Sch Med, Univ Tokyo), Shigeki Kiyonaka (Grad Sch Eng, Nagoya Univ)
Chemical tools have played important roles for visualization and control of biological phenomena in cells and tissues. At the same time, the application scope of these tools has been diversifying and tight collaboration among researchers with different research background is increasingly important. In this symposium, cutting edge scientists in the field of chemical biology who are trying to elucidate biological phenomena by using their own chemical tools or approaches will give talks as symposists or participate as organizers in order to introduce their latest research results and to discuss future prospects. Specifically, we will have talks about fluorescent probes for visualizing biomolecules in living cells (Dr. Uchinomiya and Dr. Kamiya), protein knockdown techniques (Prod. Ishikawa), control of artificial organelle by phase separation (Prof. Tsukiji), clearing chemistry of brain tissues (Prof. Tanaka), and Prof. Kiyonaka, a leading researcher in chemogenetics, and Dr. Kamiya will promote discussion as organizers.
[S06-Opening]趣旨説明
清中 茂樹1 (1. 名大院工)
[S06-1]Chemical probes for fluorescence imaging or ablation of lacZ-positive cells with single cell resolution
○Mako Kamiya1, Yasuteru Urano1,2,3 (1. Grad. Sch. Med., Univ. Tokyo, 2. Grad. Sch. Pharm. Sci., Univ. Tokyo, 3. AMED CREST)
[S06-2]Development of chemical tools for elucidation of intracellular metabolic pathways
○Shohei Uchinomiya1, Mark Weber1, Naoya Matsunaga1, Shigehiro Ohdo1, Akio Ojida1 (1. Grad. Sch. Pharm. Sci. Kyushu Univ.)
[S06-3]Degradation of cellular target proteins by small molecules
○Minoru Ishikawa1 (1. Graduate School of Life Sciences, Tohoku University)
[S06-4]Synthetic protein-assembled clusters as a new platform for manipulating signaling molecules in living cells
○Shinya Tsukiji1,2 (1. Graduate School of Engineering, Nagoya Institute of Technology, 2. Frontier Research Institute for Materials Science (FRIMS), Nagoya Institute of Technology)
[S06-5]Comprehensive 3D imaging by tissue clearing technique
○Kazuki Tainaka1 (1. BRI, Niigata Univ)
[S06-Closing]まとめ
神谷 真子1 (1. 東大院医)
