Session Details
[S15]Useful and cutting-edge tools for protein chemistry
Sun. Mar 28, 2021 9:30 AM - 11:30 AM JST
Sun. Mar 28, 2021 12:30 AM - 2:30 AM UTC
Sun. Mar 28, 2021 12:30 AM - 2:30 AM UTC
[Room D] Oral Presentation D Online
Organizer: Hino Nobumasa (Grad. Sch. Pharm. Sci., Osaka Univ.), Umehara Takashi (RIKEN)
In the field of pharmaceutical science, proteins are not only the target molecules of almost all drugs, but are also positioned as molecules that can be drugs in their own right. In recent years, various techniques for protein chemistry research have been actively developed, enabling the identification of drug target proteins by affinity probes and precise functionalization of proteins by bio-orthogonal modification methods. These technologies can maximize their potential only after they are beneficial to many researchers outside the field of expertise. In this symposium, researchers specializing in chemistry and biochemistry will come together to introduce state-of-the-art technologies, such as photo-affinity probes, drug target discovery tools, and site-directed introduction of non-natural amino acids into proteins, with examples of what applications have been made possible. The lecture on protein chemistry research from the perspective of chemistry and biochemistry will provide an opportunity to promote interdisciplinary collaborative research through discussions with pharmaceutical researchers from diverse backgrounds.
シンポジウム趣旨説明:樋野 展正(阪大院薬)
[S15-1]Application of in vivo protein photo-cross-linking method to the analysis of cancer-related protein-protein interactions.
○Nobumasa Hino1 (1. Grad. Sch. Pharm. Sci., Osaka Univ.)
[S15-2]High performance photoaffinity labeling method for reliable molecular-target identification
○Takenori Tomohiro1 (1. Fac. Pharm. Sci. Univ. Toyama)
[S15-3]Advancement of protein technology with genetic code engineering
○Kensaku Sakamoto1 (1. RIKEN)
[S15-4]Molecular mechanisms of functional proteins analyzed by unnatural fluorescent amino acids
○Akira Kawanabe1, Souhei Sakata3, Yasushi Okamura2 (1. Fac. Med., Kagawa Univ., 2. Grad. Sch. Med., Osaka Univ., 3. Fac. Med., Osaka Med. Coll.)
[S15-5]Application of artificial biotin derivative tags to search for antibody drug targets
○Haruhiko Kamada1,2,3 (1. Natl. Inst. Biomed. Innov. Health Nutr., 2. Grad. Sch. Pharm. Sci., Kyoto Univ., 3. Grad. Sch. Pharm. Sci., Osaka Univ.)
[S15-6]Mapping combinatorial chemical modification information genome-wide
○Takashi Umehara1 (1. RIKEN)
