Presentation Information

[F-23]Dimeric Fusion Loop Aptamers as Broad-Spectrum Neutralizing Candidates Against Dengue Virus Serotypes 1–4

*Islam Bakhrom Karimov1, Adeline Yeo Syin Lian1, Ryo Amano2, Kazumi Haga1, Masaki Takahashi3, Meng Ling Moi1,4 (1. Department of Developmental Medical Sciences, School of International Health, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. (Japan), 2. National Institute of Infectious Diseases (NIID) (Japan), 3. RIBOMIC Inc., Minato-ku, Tokyo 108-0071, Japan (Japan), 4. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), Tokyo, Japan (Japan))

Keywords:

Dengue virus,Flavivirus,Aptamer,SELEX,RNA therapeutics,Chimeric RNA,siRNA,Antibody-dependent enhancement

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