Presentation Information
[P-10]A stromal-immune cell interleukin-33 circuit links CD8+ T cell immunity and IgE induction in mRNA vaccination
*Kaiwen Liu1,2,3, Kouji Kobiyama1,2,3,9, Naoko Satoh-Takayama4, Tomoya Hayashi1,2,3, Burcu Temizoz1,2,3, Hideo Negishi1,2,3,5, Asuka J Tobuse1, Mai Onaga1, Atsushi Iwama6, Peter D Katsikis7, Cevayir Coban2,3,8, Ken J Ishii1,2,3 (1. Division of Vaccine Science, IMSUT (Japan), 2. International Vaccine Design Center, IMSUT (Japan), 3. The UTOPIA Center, the University of Tokyo (Japan), 4. Precision Immune Regulation RIKEN ECL Research Unit, RIKEN-IMS (Japan), 5. Laboratory of Immunology and Infection Control, IQB, the University of Tokyo (Japan), 6. Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, IMSUT (Japan), 7. Department of Immunology, Erasmus MC (Netherlands), 8. Division of Malaria Immunology, IMSUT (Japan), 9. Division of Rheumatology, Department of Medicine, University of California San Diego (USA))
Keywords:
IL-33,mRNA vaccine,CD8 T cell,IgE,Necroptosis
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