The 4th UTOPIA Symposium

*Ryutaro Kotaki¹, Daisuke Kuroda², Takeshi Inoue¹ (1. Department of Molecular Systems Immunology, The UTOPIA Center, The University of Tokyo (Japan), 2. Department of Biosciences, College of Humanities and Sciences, Nihon University (Japan))

*Nayu Shimamoto¹, Takeshi Nitta², Taku Ito-Kureha¹, Hiroshi Takayanagi¹ (1. Department of Immunology, Graduate School of Medicine, The University of Tokyo (Japan), 2. Division of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science (Japan))

*Genta Furuya¹, Fumihito Usui², Keishu Takahashi¹, Satoru Nagatoishi³, Rae Maeda⁴, Tomoki Yoshihara⁵, Kengo Sasaki¹, Rinka Kawachi¹, Ryutaro Tamano¹, Tomoya Ohno¹, Naoki Morita¹, Peng Gao¹, Fabian Eisenstein⁶, Hirofumi Kosuge³, Masumi Shirakawa⁷, Hiroyuki Arai⁸, Min Fey Chek⁵, Radostin Danev⁶, Hirotada Mori⁹, Masahide Kikkawa⁶, Shinsuke Sando⁷, Naoshi Dohmae¹⁰, Toshio Hakoshima⁵, Yuki Sugiura⁴, Kouhei Tsumoto³, Reiko Shinkura¹ (1. Laboratory of Immunology and Infection Control Institute for Quantitative Biosciences, The University of Tokyo (Japan), 2. Applied Immunology, Graduate School of Science and Technology, Nara Institute of Science and Technology (Japan), 3. Department of Bioengineering, School of Engineering, The University of Tokyo (Japan), 4. Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine (Japan), 5. Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology (Japan), 6. Graduate School of Medicine, The University of Tokyo (Japan), 7. Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo (Japan), 8. Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo (Japan), 9. Faculty of Engineering, Shinshu University (Japan), 10. Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science (Japan))

*Asuka Joy Tobuse^1,2, Kouji Kobiyama^1,3,4, Jun Tsuchida¹, Masamitsu N Asaka⁵, Daichi Utsumi⁵, Mariana Silva Almeida⁶, Yaeko Nakajima-Takagi⁷, Motohiko Oshima⁷, Tomoya Hayashi^1,3,8, Burcu Temizoz^1,3,8, Etsushi Kuroda⁹, Cevayir Coban^2,3,6,8, Yasuhiro Yasutomi^5,10, Atsushi Iwama^2,7, Ken J Ishii^1,2,3,8 (1. Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo (Japan), 2. Department of Computational Biology and Medical Science, Graduate School of Frontier Sciences, The University of Tokyo (Japan), 3. International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo (Japan), 4. Division of Rheumatology, Department of medicine, University of California San Diego, La Jolla, California (USA), 5. Laboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba (Japan), 6. Division of Malaria Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo (Japan), 7. Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, University of Tokyo (Japan), 8. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo (Japan), 9. Department of Immunology, Hyogo Medical University School of Medicine, Nishinomiya, Hyogo (Japan), 10. Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Hokkaido (Japan))

*Kaiwen Liu^1,2,3, Kouji Kobiyama^1,2,3,9, Naoko Satoh-Takayama⁴, Tomoya Hayashi^1,2,3, Burcu Temizoz^1,2,3, Hideo Negishi^1,2,3,5, Asuka J Tobuse¹, Mai Onaga¹, Atsushi Iwama⁶, Peter D Katsikis⁷, Cevayir Coban^2,3,8, Ken J Ishii^1,2,3 (1. Division of Vaccine Science, IMSUT (Japan), 2. International Vaccine Design Center, IMSUT (Japan), 3. The UTOPIA Center, the University of Tokyo (Japan), 4. Precision Immune Regulation RIKEN ECL Research Unit, RIKEN-IMS (Japan), 5. Laboratory of Immunology and Infection Control, IQB, the University of Tokyo (Japan), 6. Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, IMSUT (Japan), 7. Department of Immunology, Erasmus MC (Netherlands), 8. Division of Malaria Immunology, IMSUT (Japan), 9. Division of Rheumatology, Department of Medicine, University of California San Diego (USA))

*BURCU TEMIZOZ^1,2,6,7, Nobuyoshi Kobayashi^2,3, Yuta Ohira^2,3, Kou Hioki¹, Mai Onaga¹, Tomoya Hayashi^1,2,6,7, Michelle Sue Jann Lee⁵, Takayuki Horii³, Cevayir Coban^4,5,6,7, Kouji Kobiyama^1,2,6,7, Ken J Ishii^1,2,4,6,7 (1. Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo (IMSUT), 4-6-1, Tokyo, Japan (Japan), 2. Center for Adjuvant and Vaccine Research, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8, Osaka, Japan (Japan), 3. Central Research Laboratories, Zeria Pharmaceutical Co., Ltd., 2512-1 Numagami, Oshikiri, Kumagaya-shi, Saitama, Japan (Japan), 4. WPI Immunology Frontier Research Center (IFReC), Osaka University, 3-3-1, Osaka, Japan (Japan), 5. Division of Malaria Immunology, Department of Microbiology and Immunology, The Institute of Medical Science (IMSUT), The University of Tokyo, 4-6-1, Tokyo, Japan (Japan), 6. International Vaccine Design Center (VDesC), The Institute of Medical Science (IMSUT), The University of Tokyo, 4-6-1, Tokyo, Japan (Japan), 7. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), The University of Tokyo, Tokyo 108-8639, Japan. (Japan))

*Calvin Duong^1,4, Yui Honjo¹, Mifumi Goto¹, Jisuk Ko¹, David Pattinson⁵, Lavanya Babujee⁵, Gabriele Neumann⁵, Seiya Yamayoshi^1,2,3,4, Yoshihiro Kawaoka^1,3,4,5 (1. Division of Virology, Institute of Medical Science, University of Tokyo, Japan (Japan), 2. International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo (Japan), 3. Research Center for Global Viral Infections, National Center for Global Health and Medicine Research Institute (Japan), 4. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (Japan), 5. Department of Pathobiological Sciences, School of Veterinary Medicine (USA))

*Yuka Kawazu¹, Shohei Hori¹, Ruka Setoguchi¹ (1. Laboratory for Immunology and Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo (Japan))

*Taisuke Narazaki¹, Daisuke Sugiura¹, Il-mi Okazaki¹, Takumi Maruhashi,¹, Kenji Shimizu¹, Taku Okazaki¹ (1. Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, University of Tokyo (Japan))

*Mizuki Yamamoto¹, Yoko Hirayama¹, Jun-ichiro Inoue², Yasushi Kawaguchi^3,1,2, Xuenan Xuan¹ (1. Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo (Japan), 2. The University of Tokyo Pandemic preparedness, Infection and Advanced research center (UTOPIA), The University of Tokyo (Japan), 3. Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo (Japan))

*Hideo Negishi^1,2,3,4, Yusuke Wada¹, Yoshitaka Shirasaki⁵, Tomoya Hayashi^1,2,4, Yuji Kubota⁶, Tomio Iwasaki⁷, Mina Kurosawa¹, Tatsuma Ban⁸, Daisuke Muto⁹, Yusuke Suenaga⁹, Taichi Kojima¹, Yuzuki Matsuda¹, Sean Lord Irish¹, Kosuke Dodo^10,11, Toru Suzuki¹², Mai Yamagishi¹³, Burcu Temizoz^1,2,4, Atsushi Yoshimori¹⁴, Chisato Kanai¹⁵, Yoji Nagasaki¹⁶, Masaki Ohmuraya¹⁷, Tomohiko Tamura^8,18, Atsushi Iwama^4,19,20, Toshifumi Inada^4,12, Etsushi Kuroda²¹, Kouji Kobiyama^1,2,4, Noriko Toyama-Sorimachi², Mutsuhiro Takekawa^4,6,22, Cevayir Coban^2,4,23, Ken J Ishii^1,2,4 (1. Department of vaccine science, The UTOPIA Center, The University of Tokyo (Japan), 2. International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan (Japan), 3. Laboratory of Immunology and Infection Control, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan (Japan), 4. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), The University of Tokyo, Tokyo, Japan (Japan), 5. Division of Photonic Imaging, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan (Japan), 6. Division of Cell Signaling and Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan (Japan), 7. esearch and Development Group, Hitachi, Ltd., Ibaraki, Japan (Japan), 8. Department of Immunology, Yokohama City University Graduate School of Medicine, Kanagawa, Japan (Japan), 9. Laboratory of Evolutionary Oncology, Chiba Cancer Center Research Institute, Chiba, Japan (Japan), 10. Synthetic Organic Chemistry Laboratory, RIKEN Cluster for Pioneering Research, Saitama, Japan (Japan), 11. Catalysis and Integrated Research Group, RIKEN Center for Sustainable Resource Science, Saitama, Japan (Japan), 12. Division of RNA and gene regulation, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan (Japan), 13. Live Cell Diagnosis, Ltd., Saitama, Japan (Japan), 14. Institute for Theoretical Medicine, Inc., Kanagawa, Japan (Japan), 15. INTAGE Healthcare, Inc., Osaka, Japan (Japan), 16. Department of Pharmacy, NHO Kyushu Medical Center, Fukuoka, Japan (Japan), 17. Department of Genetics, School of Medicine, Hyogo Medical University, Hyogo, Japan (Japan), 18. Advanced Medical Research Center, Yokohama City University, Kanagawa, Japan (Japan), 19. Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan (Japan), 20. Laboratory of Cellular and Molecular Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (Japan), 21. Department of Immunology, Hyogo Medical University School of Medicine, Hyogo, Japan (Japan), 22. Medical Proteomics Laboratory, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan (Japan), 23. Division of Malaria Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan (Japan))

*Mariana Silva Almeida^1,2,3, Florian Dubois^1,2,3, Hiroaki Matsumori^1,2,3, Reiko Shinkura^3,4, Takeshi Inoue⁵, Jun Kunisawa⁶, Ken J Ishii^2,3,7, Cevayir Coban^1,2,3 (1. Department of Malaria Immunology, Institute of Medical Science, The University of Tokyo (Japan), 2. International Vaccine Design Center, Institute of Medical Science (IMSUT), The University of Tokyo (Japan), 3. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), The University of Tokyo (Japan), 4. Laboratory of Immunology and Infection Control, Research Division for Quantitative Life Sciences (IQB), The University of Tokyo (Japan), 5. Department of Molecular Systems Immunology, The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA) (Japan), 6. Laboratory of Vaccine Materials and Laboratory of Gut Environmental System,Microbial Research Center for Health and Medicine,National Institutes of Biomedical Innovation Health and Nutrition(NIBIOHN) (Japan), 7. Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science (IMSUT), The University of Tokyo (Japan))

*Takuma Shibata¹, Emi Nishimura¹, Kensuke Miyake² (1. Division of Aging and Regeneration, The Institute of Medical Science, The University of TOKYO (Japan), 2. Synergy Institute for Futuristic Mucosal Vaccine Research and Development, Chiba University (Japan))

*Hiroaki Matsumori^1,2,3, Mariana Silva Almeida^1,2,3, Yuya Yoshioka⁴, Pinarlik Fatihan^1,2,3, Kazunori Sasaki^2,3,4, Ken Ishii^2,3,4, Cevayir Coban^1,2,3 (1. Division of Malaria Immunology, Department of Microbiology and Immunology, The Institute of Medical Science (IMSUT), The University of Tokyo, Japan (Japan), 2. International Vaccine Design Center, Institute of Medical Science (IMSUT), The University of Tokyo, Japan (Japan), 3. The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), The University of Tokyo, Japan (Japan), 4. Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science (IMSUT), The University of Tokyo, Japan (Japan))

*Suqi WANG¹, Ryunosuke MURO², Taku KUREHA¹, Takeshi NITTA², Hiroshi TAKAYANAGI¹ (1. Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo (Japan), 2. Division of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science (Japan))

*Yuji Kubota¹, Mutsuhiro Takekawa¹ (1. Division of Cell Signaling and Molecular Medicine, Institute of Medical Science, The University of Tokyo (Japan))

*Shiho Chiba^1,3,2, Maki Kiso¹, Seiya Yamayoshi^3,1,4, Yoshihiro Kawaoka^1,2,3,4 (1. The UTOPIA Center, The University of Tokyo (Japan), 2. University of Wisconsin-Madison (USA), 3. International Virus Infectious Disease Research Center, Japan Institute for Health Security (Japan), 4. Division of Virology, Institute of Medical Science, University of Tokyo (Japan))

*Yuji Tsunekwa¹, Ken Sugo¹, Takashi Okada¹ (1. Institute of Medical Science, The University of Tokyo DMMG (Japan))

*Hirotatsu Kojima¹ (1. Drug Discovery Initiative, Graduate School of Pharmaceutical Sciences, The University of Tokyo (Japan))

*Jun Nakamura¹, Kaya Miyazaki¹, Shintaro Kobayashi², Yasutaka Minegishi³, Shingo Kosugi³, Kohei Takeshita⁴, Saeko Ishida¹, Kazuto Yoshimi¹, Hiroaki Kariwa², Yoshihiro Kawaoka⁵, Tomoji Mashimo¹ (1. Division of Genome Engineering, Institute of Medical Science, The University of Tokyo (Japan), 2. Laboratory of Public Health, Faculty of Veterinary Medicine, Hokkaido University (Japan), 3. Nippon Gene Co., Ltd. (Japan), 4. Life Science Research Infrastructure Group, RIKEN SPring-8 Center, RIKEN (Japan), 5. Department of Virology, The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA) (Japan))

*Yoshiki Saiki¹, Kazuto Yoshimi², Masahiko Ito³, Tetsuro Suzuki³, Tomoji Mashimo¹ (1. Department of Animal Genetics, The UTOPIA Center, The University of Tokyo (Japan), 2. Laboratory Animal Science, Graduate School of Medicine and Faculty of Medicine, Kyoto University (Japan), 3. Department of Microbiology and Immunology, Hamamatsu University School of Medicine (Japan))

*Shotaro Torii¹, Rika Hirano^2,3, Kazuto Yoshimi^2,3, Tomoji Mashimo³, Kumiko Oguma¹ (1. Departiment of Urban Engineering, School of Engineering, The University of Tokyo (Japan), 2. Institute of Laboratory Animals Graduate School of Medicine, Kyoto University (Japan), 3. Institute of Medical Science, The University of Tokyo, The University of Tokyo (Japan))

*Kilian Colas¹, Abelhakim El Youbi¹, Naoakusa Fujimura¹, Hiroaki Suga¹ (1. Department of Chemistry, Graduate School of Science, The University of Tokyo (Japan))

*Yoshihiro Minagawa¹, Hiroyuki Noji¹ (1. Noji Laboratory, Department of Applied Chemistry, Graduate School of Engineering, The University of Tokyo (Japan))

*Tatsuyuki Yoshii¹, Fumiya Ito¹, Hirohide Saito¹ (1. Instititute for Quantitative Biosciences, The University of Tokyo (Japan))

*Mie Kobayashi-Ishihara¹, Naoko Fujita¹, Ryo Komorizono¹, Masakaze Hamada¹, Yuki Furuse¹ (1. Department of Microbiology and Infection, The UTOPIA Center, The University of Tokyo (Japan))

*Go Sato^1,2,3, Ryuya Edahiro^2,3, Yuji Yamamoto², Tomohiro Yata², Kotaro Ogawa², Kyuto Sonehara^1,2,3, Ryunosuke Saiki⁴, Shinichi Namba^1,2,3, Takafumi Ojima^1,2,3, Yuya Shirai^2,3, Koichi Matsuda¹, Seishi Ogawa⁴, Tatsusada Okuno², Noriko Isobe⁵, Ho Namkoong⁶, Toshimasa Yamauchi¹, Takashi Kadowaki⁷, Atsushi Kumanogoh², Yukinori Okada^1,2,3 (1. Graduate School of Medicine, the University of Tokyo (Japan), 2. Graduate School of Medicine, the University of Osaka (Japan), 3. RIKEN Center for Integrative Medical Sciences (Japan), 4. Graduate School of Medicine, Kyoto University (Japan), 5. Graduate School of Medical Sciences, Kyusyu University (Japan), 6. Keio University School of Medicine (Japan), 7. Toranomon Hospital (Japan))

*Yichen Jiang¹, Ayumu Tsubosaka¹, Kyohei Sano¹, Miwako Kakiuchi¹, Daisuke Komura¹, Hiroto Katoh³, Tetsuo Ushiku², Ishikawa Shumpei^1,3 (1. Department of Preventive Medicine, The University of Tokyo (Japan), 2. Department of Pathology, The University of Tokyo (Japan), 3. Division of Pathology, National Cancer Center Japan (Japan))

*Ryo Matsunaga¹, Tomomi Aoki¹, Kouhei Tsumoto^1,2 (1. School of Engineering, The University of Tokyo (Japan), 2. Institute of Medical Science, The University of Tokyo (Japan))

*Chihiro NISHI¹, Kaori MUTO^1,2 (1. Department of Public Policy, The Institute of Medical Science, The University of Tokyo (Japan), 2. Laboratory for Biomedical Ethics and Co-design, RIKEN Center for Integrative Medical Sciences (Japan))

*Jinjue Liang¹, Takuma Shibata¹, Kyosuke Asakawa¹, Yuhei Maruzuru², Yasushi Kawaguchi², Emi Nishimura¹ (1. Department of Aging and Regeneration, The UTOPIA Center, The University of Tokyo (Japan), 2. Division of Molecular Virology,The University of Tokyo (Japan))