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[WS20-06-P]An Engineered Probiotic Produces a Type III Interferon IFNL1 and Reduces Inflammations in in vitro Inflammatory Bowel Disease Models

Koon Jiew Eri Chua1,2,3,4, Hua Ling1,2,3,4, In Young Hwang1,2,3,4, Hui Ling Lee1,2,3,4, John C March5, Yung Seng Lee1,2,6, Matthew Wook Chang1,2,3,4 (1.National University of Singapore, NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Singapore, Singapore, 2.National University of Singapore, Synthetic Biology Translational Research Programme, Singapore, Singapore, 3.National University of Singapore, Department of Biochemistry, Singapore, Singapore, 4.National University of Singapore, Wilmar-NUS Corporate Laboratory, Singapore, Singapore, 5.Cornell University, Department of Biological and Environmental Engineering, Ithaca, NY, 6.National University of Singapore, Department of Paediatrics, Singapore, Singapore)

キーワード:

Inflammatory Bowel Disease、Interferon Lambda、Regulatory T cells、Probiotics

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