[WS(P)26] Systemic Immune Diseases

[WS26-19-P] Understanding the pathogenesis of Aicardi-Goutières syndrome-like encephalopathy caused by mutations in the RNA-editing enzyme ADAR1.

^○Hyebin Yoo¹, Reiichi Sugihara², Taisuke Nakahama^1,2,3,4, Yuki Kato^1,2,3, Yukio Kawahara^1,2,3,4,5 (1.Department of RNA Biology and Neuroscience, Graduate School of Frontier Biosciences, Osaka University, 2.Department of RNA Biology and Neuroscience, Graduate School of Medicine, Osaka University, 3.Integrated Frontier Research for Medical Science Division and RNA Frontier Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, 4.Center for Infectious Disease Education and Research (CiDER), Osaka University, 5.Genome Editing Research and Development Center, Graduate School of Medicine, Osaka University)

キーワード：

Autoinflammation、ISGs、type1 IFN、Z-DNA/RNA

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