講演情報

[WS26-26-O/P]Isoliquiritigenin inhibits activation of NLRP3 inflammasome with CAPS mutations by suppressing caspase-1 activation and mutant NLRP3 aggregation

Koudai Kani1, Hiroe Honda2, Kiyoshi Takatsu2, Yoshinori Nagai1 (1.Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 2.Toyama Prefectural Institute for Pharmaceutical Research)

キーワード:

NLRP3 inflammasome、Cryopyrin-associated periodic syndromes、isoliquiritigenin、macrophage

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