セッション詳細
[WS(P)24]Dendritic cells: Molecular basis for regulation of their differentiation, activation, and function
2024年12月5日(木) 15:00 〜 15:45
Poster 2
[WS24-01-P]Roles of transcription factors PU.1 and SpiB, and epigenetic regulation in commitment between conventional dendritic cells and plasmacytoid dendritic cells
○Naoto Ito1, Mayumi Hirakawa2, Weiting Zhao1, Natsuki Minamikawa1, Mayuka Katagiri1, Ryusei Tokita1, Ryosuke Miura1, Kazuki Nagata1, Tomokatsu Ikawa2, Chiharu Nishiyama1 (1.Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 2.Research Institute for Biomedical Sciences, Tokyo University of Science)
[WS24-02-O/P]The role of splenic CD8α+CD103+ cDC1 in the maintenance of immune homeostasis
○Junko Morimoto1, Hiroyuki Kondo1, Rinka OKahisa1, Li Hui1, Daisuke Kurotaki2, Koji Yasutomo1 (1.Department of Immunology and Parasitology, Graduate School of Medicine, Tokushima University, 2.Laboratory of Chromatin Organization in Immune Cell Development, International Research Center for Medical Sciences, Kumamoto University)
[WS24-03-P]The transcription factor BATF is involved in nucleic acid-induced maturation of dendritic cells
○Tomoko Asatsuma-Okumura, Ryuji Owada, Shoko Kuroda, Masaaki Hashiguchi, Yoshiko Iwai (Nippon Medical School)
[WS24-04-O/P]SIRPα promotes the survival of cDC2s by preventing their activation and induction of an nuclear receptor family protein
○Satomi Komori1,2, Takenori Kotani2, Yoji Murata2, Takashi Matozaki1,2, Yasuyuki Saito2 (1.Division of Biosignal Regulation, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, 2.Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine)
[WS24-05-P]Butyric acid suppresses migration of monocyte derived Dendritic Cell by inhibiting Actin polymerization via mDia1 inhibition
○Takumi Nagamoto1,2, Keisuke Nishimura1,2, Hiroyuki Murabe2, Jun Saegusa1,2 (1.Kobe University Graduate School of Medicine Department of Immunology, 2.Kurashiki Central Hospital Department of Endocrinology and Rheumatology)
[WS24-06-P]Regulatory Mechanisms of Gene Expression and Development of Conventional Dendritic Cell and Plasmacytoid Dendritic Cell by Short-Chain Fatty Acids
○Weiting Zhao1, Kazuki Nagata1, Naoto Ito1, Ryusei Tokita1, Yuta Yahagi1, Hotaka Okamura1, Osamu Kaminuma2, Chiharu Nishiyama1 (1.Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science., 2.Department of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University.)
[WS24-07-P]Immunosuppressive effect of perilla leaf aroma components
○Ryusei Tokita, Naoto Ito, Hikaru Okada, Sakaura Noguchi, Ayaka Sugihara, Kazuki Nagata, Chiharu Nishiyama (Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science.)
[WS24-08-O/P]Morphological abnormalities of induced pluripotent stem cell-derived dendritic cells (iPSC-derived DCs) in MIRAGE syndrome with SAMD9 mutation
○Hidetoshi Hagiwara1, Masataka Ito2, Kanako Mitsui-Sekinaka1, Kunihiko Moriya1, Yujin Sekinaka1, Yuri Kawasaki3, Yohko Kitagawa3, Kanako Tanase-Nakao4, Satoshi Narumi5, Megumu K. Saito3, Shigeaki Nonoyama1, Kohsuke Imai1 (1.Department of Pediatrics, National Defense Medical College, 2.Department of Developmental Anatomy and Regenerative Biology, National Defense Medical College, 3.Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, 4.Department of Molecular Endocrinology, National Center for Child Health and Development, 5.Department of Pediatrics, Keio University School of Medicine)
[WS24-09-O/P]The role of mitochondria damage in Imiquimod-induced psoriasis
○Daisuke Ori1, Haruna Okude1, Riko Konishi1, Takumi Kawasaki2, Taro Kawai1,3 (1.Laboratory of Molecular Immunobiology, Division of Biological Science, Nara Institute of Science and Technology, 2.Department of Immune Dynamics in Viral Infections, National Research Center for the Control and Prevention of Infectious Diseases, Nagasaki University, 3.Life Science Collaboration Center (LiSCo), Nara Institute of Science and Technology (NAIST))
[WS24-10-O/P]STAT1 binding element in the Irf8 promoter is required for inducing a distinct inflammatory dendritic state during intracellular pathogen infection
○Kenta Kikuchi1, Wataru Kawase2, Yusuke Tsujimura3, Fuki Kudo4, Keita Saeki4, Takayuki Yoshimoto5, Manabu Ato3, Keiko Ozato4, Tomohiko Tamura2, Daisuke Kurotaki1 (1.Laboratory of Chromatin Organization in Immune Cell Development, International Research Center for Medical Sciences (IRCMS), Kumamoto University, 2.Department of Immunology, Yokohama City University Graduate School of Medicine, 3.Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, 4.Program in Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 5.Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University)
[WS24-11-O/P]Genetic ablation of the protein tyrosine phosphatase Shp1 in CD11c+ cells improves insulin resistance
○Yoichi Imai1, Yoriaki Kaneko1, Masato Kinoshita1, Junya Suwa1, Mitsuharu Watanabe2, Yasuyuki Saito3, Hiroshi Ohnishi4, Takashi Matozaki3, Keiju Hiromura1 (1.Gunma University Graduate School of Medicine department pf Nephrology and Rheumatology, 2.NHO Takasaki general medical center department of Nephrology and Rheumatology, 3.Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, 4.Department of Laboratory Scineces, Gunma University Graduate School of Healthe Sciences)
[WS24-12-P]A group Streptococcus-Derived Proteins and Host Factors Contributing to Innate Inflammation in murine Dendritic Cells
○Natsuo Yamamoto1,2, Tsuyoshi Suzuki2, Hideki Yamamoto3, Suguru Ohmiya1, Masamichi Katsumi1, Hidekazu Nishimura1, Ken Iseki2 (1.Sendai Virus Center, 2.Department of Emergency and Critical Care Medicine, Fukushima Medical University, 3.Department of Medical Technology, Graduate School of Health Sciences, Niigata University, Niigata, Japan)
[WS24-13-P]Dendritic cell decrease in peritoneal exudate cells in liver cirrhosis patients
○Shiori Kaji1, Izumi Sasaki2, Takashi Kato3, Daisuke Okuzaki4, Sadahiro Iwabuchi5, Shinichi Hashimoto5, Shin-Ichiroh Saitoh6, Tsuneyasu Kaisho2 (1.Second Department of Internal Medicine, Wakayama Medical University, 2.Department of Immunology, Institute of Advanced Medicine, Wakayama Medical University, 3.Department of Rheumatology and Clinical Immunology, Wakayama Med Univ, 4.WPI-Immunology Frontier Research Center, Osaka Univ, 5.Department of Molecular Pathophysiology, Institute of Advanced Medicine, Wakayama Medical University, 6.Department of Intractable Disorders, Institute of Advanced Medicine, Wakayama Medical University)
[WS24-14-P]Role of migratory dendritic cells in mRNA vaccine-induced CTL differentiation
○Ryunosuke Muro1, Suqi Wang2, Taku Ito-Kureha2, Takeshi Nitta1, Hiroshi Takayanagi2 (1.Division of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science, 2.Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo,)
[WS24-15-O/P]Identification of CIITA degron and ubiquitination site by FBXO11
○Yusuke Kasuga1,3, Royota Ouda1, Masashi Watanabe2, Xin Sun1, Miki Kimura1, Atsuki Takeishi1,3, Tsutomu Tanaka1,3, Shigetsugu Hatakeyama2, Koichi Kobayashi1,3 (1.Department of Immunology, Faculty of Medicine, Hokkaido University, 2.Department of Biochemistry, Faculty of Medicine, Hokkaido University, 3.Hokkaido University Institute for Vaccine Research and Development)
[WS24-16-P]The differentiation of dendritic cells and macrophages in hu-PBL-hIL-4-Tg mouse
○Ayako Hirota1, Shino Oshima2, Yuki Hoshino2, Soga Yamada2, Banri Tsuda3, Atsushi Yasuda4, Ryoji Ito5, Akiko Kanamori6,7, Tomotaka Mabuchi1, Hitoshi Ishimoto8, Takashi Shiina2, Yosie Kametani2 (1.Department of Dermatology, Tokai University School of Medicine, 2.Department of Molecular Life Science, Tokai University School of Medicine, 3.Department of Palliative Medicine, Tokai University School of Medicine, 4.Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, 5.Central Institute for Experimental Medicine and Life Science, 6.Dept. of Bioeng., Sch. of Engineering, Tokai Univ., Inst. Adv. Biosci., Tokai Univ., 7.Department of Bioengineering, School of Engineering, Tokai University Institute of Advanced Biosciences, Tokai University, 8.Department of Obstetrics and Gynecology, Tokai University School of Medicine)