講演情報
[17p-C31-4]Design and Fabrication of Deep Trench Probe for Lactate Sensing to Analyze Cancer Cells in Brain Tissue
〇(M2)Shinki Kyuu1, Naoki Iwanuma1, Shutaro Oba1, Kazushi Tsuji2, Takafumi Fukushima1,2, Tetsu Tanaka1,2 (1.TOHOKU Univ., 2.Tohoku Univ.)
キーワード:
bio sensor、lactate sensor
Glioblastoma multiforme (GBM) is a highly lethal grade IV brain tumor. Despite standard treatment like surgery, the 5-year survival rate remains only 7.2%. The infiltrative nature of GBM makes complete resection at the cellular level extremely challenging. Due to the Warburg Effect, elevated lactate levels in brain tissue are a key indicator of the presence of cancer cells. A proposed brain-implantable probe aims to help define tumor boundaries during surgery by detecting lactate levels in real-time with high precision.
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