講演情報

[ESY2-5]Surgical stress response in Kangduo versus Da Vinci robot-assisted for colorectal cancer

Yunxiao Liu, Yuliuming Wang, Guiyu Wang (Department of colorectal cancer surgery, the Second Affiliated Hospital of Harbin Medical University)
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Background: The efficacy and safety of Kangduo robotic technology in colorectal cancer (CRC) surgery have been fully verified. However, no studies have yet reported its short-term impact on surgical stress response.
Methods: This study conducted a post-hoc analysis using the data from a previous non-inferiority randomized controlled trial (ChiCTR2200063172). Patients with stage I-III CRC who underwent robotic-assisted radical colorectal cancer surgery between June 2022 and May 2023 were included. Participants were randomized 1:1 to receive either Kangduo or Da Vinci robotic-assisted surgery. The primary outcomes were changes in systemic stress response markers, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), white blood cell count (WBC), hemoglobin (HB), neutrophil count (NEU), albumin (ALB), creatinine (CR), blood urea nitrogen (BUN), and lymphocyte count (LY).
Results: A total of 100 CRC patients were enrolled: 50 in the Kangduo robotic-assisted group and 50 in the Da Vinci robotic-assisted group. No significant differences were observed between the two groups in any of the measured stress response markers. Similar findings were noted in the subgroup analysis of patients without postoperative complications.
Conclusion: Kangduo robotic-assisted CRC surgery induces systemic stress response changes comparable to those observed with the Da Vinci robotic system.