[C04] Systems Biology

[C04-02] Timescale Decomposition of Linear Chemical Reaction Networks

*Hideshi Ooka¹, Hirokazu Komatsu², Sahaya Vijay Jeyaraj¹, Ryuhei Nakamura^1,3 (1. RIKEN (Japan), 2. Kindai Univ. (Japan), 3. Science Tokyo (Japan))

Keywords:

Chemical Reaction Networks,Autocatalysis,Origin of Life

Chemical reaction networks arise in various contexts, not only in metabolic networks composed of enzymatic reactions, but also in general catalytic reactions including both biological, artificial, and geochemical systems. Therefore, understanding what determines their efficiency and longevity is an important consideration to understand how chemicals and materials are interconverted on our planet. In particular, such catalytic networks have a finite lifetime, due to the existence of side reactions which dissipate chemical species outside the network. In this talk, we will focus on a chemical reaction network consisting of first-order reactions, which is used as a model of catalysis. By separating the time scale between the fast catalytic process and the slow, dissipation process, we propose how there may be a tradeoff relationship between the rates and lifetime of catalytic reaction networks.