[C04] Systems Biology

[C04-03] Calculating the Lifetime of Autocatalytic Chemical Reaction Networks

*Sahaya Vijay Jeyaraj¹, Hirokazu Komatsu², Ryuhei Nakamura^1,3, Hideshi Ooka¹ (1. RIKEN (Japan), 2. Kindai University (Japan), 3. Science Tokyo (Japan))

Keywords:

Chemical reaction network,Autocatalysis,Origin of life

A theoretical model was developed to evaluate the lifetime of autocatalytic chemical reaction networks, which is considered to be a requirement for chemical evolution and the origin of Life. So far, five different types of autocatalytic motifs have been identified, but predicting the lifetime and stability of these networks remains difficult. In this work, we propose a first-order chemical reaction network containing n species (X₁, X₂, X₃, …, X_n) and have calculated how the lifetime of each network may change depending on the presence of not only autocatalytic pathways, but also dissipative pathways such as diffusion.