Presentation Information

[C13-04]Treatment Simulation for ALK+ NSCLC: Mathematical Modelling with Drug-Tolerant Persister Cells

*Yoshitaka Kozaki1, Ryohei Katayama2, Shingo Iwami1 (1. Interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan (Japan), 2. Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan (Japan))

Keywords:

Treatment simulation,Mathematical modeling,ALK-positive Non-Small Cell Lung Cancer,Tumor growth,Resistant mutation,PK/PD model,Persister model,Stochastic simulation

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