Presentation Information
[POS-01]Prediction of human PK of drug antibody in a human PBPK model using scaling factors obtained from cynomolgus PK
*TAICHI AKAHOSHI1, Yasunori Komori1, Yoshie Takashima2, Koki Kibe2, Sotaro Naoi3, Kohji Nagano2, Kimio Terao1, Tatsuhiko Tachibana1 (1. Pharmaceutical Science Department, Translational Research Division, Chugai Pharmaceutical Co., Ltd., Yokohama-shi, Japan. (Japan), 2. Research Division, Chugai Pharmaceutical Co. Ltd., 216 Totsuka-cho, Totsuka-ku, Yokohama, Kanagawa, 244-8602, Japan. (Japan), 3. Research Division, Chugai Pharmabody Research, Singapore, Singapore. (Singapore))
Keywords:
PBPK,modeling and simulation,human,antibody
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