Presentation Information
[PT04-01]Mathematical Modeling for Anticancer Drug Therapy
*Il Hyo Jung1 (1. Pusan National University (Korea))
Keywords:
Cancer
Mathematical modeling of anticancer drug therapy has a history of more than 50 years. This research field has contributed to the development of ideas about drug therapy scheduling, multi-drug protocols, the recruitment and synchronization of normal cells and cancer cells etc. The phenomena and relationships that relate a drug dose to its concentration in plasma or its effect on cancer or normal cells are defined by the so-called pharmacokinetics (PK) and pharmacodynamics (PD). PK describes the variation between dose and concentration in plasma, while PD describes the effect of a given concentration on cell viability. In this talk, I will introduce some biological background and mathematical modeling techniques in this field that have the potential to contribute to anticancer drug therapy and consider several topics, which may help improve the situation in the mathematical approach.