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Mon. Jul 7, 2025

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Differentiable simulation of neurodegenerative disease progression for brain image-based inverse modeling

Another new wave is approaching mathematical biology: its full-scale entry into the field of medicine. The era has truly arrived where mathematical research, which was previously confined to theoretical studies, is now actively collaborating with medical doctors and researchers in the field. Medicine is broadly divided into basic medicine and clinical medicine. Basic medicine can be viewed as fundamental biology, aiming to unravel the core principles of life in order to save human lives. If basic medicine focuses on the future, striving to be useful ‘someday,’ clinical medicine focuses on the present, aiming to treat patients ‘now.’ To tackle these different but closely related fields of medicine, mathematical approaches must also adopt different perspectives. In this initiative, we share cutting-edge research at the forefront of mathematical medicine, bringing transformation through new approaches that integrate data and mathematical modeling.

Transformation and Integration of Data and Modeling in Medicine

Joint Meeting of Asian Conference for Mathematical Biology and Annual Meeting of Japanese Society for Mathematical Biology (ACMB-JSMB2025)

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[SS21-03]Differentiable simulation of neurodegenerative disease progression for brain image-based inverse modeling

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