Session Details

[MS11]Dynamics of Pattern Formation and Morphogenesis in Biological Systems

Fri. Jul 11, 2025 10:10 AM - 11:50 AM JST
Fri. Jul 11, 2025 1:10 AM - 2:50 AM UTC
Room 06
Chair:Jinghao Chen(Kyoto University, Japan), Min-Jhe Lu(National Tsing Hua University, Taiwan)
In biological systems, pattern formation and morphogenesis emerge from mechanical forces, geometric constraints, and biochemical regulation. By integrating mathematical modeling, computational simulations, and biological experiments, researchers are revealing how living structures take shape. This mini-symposium gathers experts in applied mathematics, computational biology, and experimental biophysics to discuss cutting-edge progress in morphogenetic pattern formation.
Geometric constraints shape epithelial tissue dynamics. Growth-induced stresses and material properties produce digit-like features, while imaging and modeling—ranging from optimal transport to phase-field methods—quantify tissue evolution. These approaches link mechanical forces to cellular behavior. Morphological interfacial dynamics also highlight topological transitions, from nuclear reorganization to tumor growth.
Integrating theory and experimentation, this symposium spotlights interdisciplinary collaboration to address biological complexity. Talks will feature mathematical and computational tools—stochastic methods, differential equations, and more—for multiscale analysis. We aim to spark collaborations, inspire innovative strategies, and deepen our understanding of morphogenesis.

[MS11-01]Geometric Constraints and Their Role in Epithelial Folding Patterns

*Yasuhiro Inoue1, Kaito Kuninishi1, Tomohiro Mimura1 (1. Kyoto University (Japan))

[MS11-02]In situ stemness assessment of human pluripotent stem cells through deep-learning-assisted holotomography

*Ki-Jun Yoon1, Hoewon Park1, Geon Kim1, Yongkeun Park1 (1. KAIST (Korea))

[MS11-03]Emergence of digit-like structures through mechanical instabilities: A hybrid computational and experimental study

*Antoine Diez1,2, Rio Tsutsumi2, Steffen Plunder2 (1. RIKEN iTHEMS (Japan), 2. ASHBi, Kyoto University (Japan))

[MS11-04]Imaging data-based model description tool using optimal transport theory and phase-field method

*Tsubasa Sukekawa1, Toshiaki Yachimura2, Sungrim Seirin-Lee1,3 (1. Institute for the Advanced Study of Human Biology, Kyoto University Institute for Advanced Study, Kyoto University (Japan), 2. Mathematical Science Center for Co-creative Society, Tohoku University (Japan), 3. Graduate School of Medicine, Kyoto University (Japan))

[MS11-05]Mechanical and Chemical Interactions in Tumor Growth: Insights from Mathematical Modeling

*Min-Jhe Lu1, John Lowengrub2 (1. National Tsing Hua University (Taiwan), 2. University of California, Irvine (United States of America))