[1N12-15] Separation Technique

4:10 PM - 4:25 PM JST(7:10 AM - 7:25 AM UTC)

[1N13] Development of astatine-211 dry recovery process by evaporation with aerosol(3)Overall concept for Practical Application of At-211

*ATSURO HAYAKAWA¹, YASUHIRO SUZUKI¹, MASARU YUHARA¹, KEISUKE TSUKADA¹, HIROSHI OKABE¹, YU YAMASHITA¹, Atsushi Toyoshima³, Mitsuhiro Fukuda², Atsushi S^3,4, TAKASHI NAKANO² (1. Toshiba ESS, 2. RCNP, Osaka Univ, 3. IRS, Osaka Univ., 4. Osaka Aoyama Univ.)

Keywords:

Astatine,Aerosol

Currently, development of cancer drugs using various radionuclides is underway, and astatine-211 (211At), an alpha-ray nuclide, is a promising candidate nuclide. We are developing a 211At separation and recovery system using the “Aerosol method”, The Bi target containing 211At is heated in which produced by nuclear transmutation by an accelerator, and the vaporized 211At is attached to aerosol particles and collected by a filter. The results of the development are outlined, and a concept for the future practical use of 211At is also reported.We are currently developing a technology to separate and recover 211At from the target after irradiation. We are aiming for the practical application of At pharmaceuticals with this technology as the key. First, a system that can supply At for clinical trials will be established, and once a stable supply is realized and the drug market is established, a strategy to establish a large-scale manufacturing base and mass supply is envisioned.