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[1P-131]Chronic administration of SYK-623, an inverse agonist of δ opioid receptor, prevents the reduction of diazepam sensitivity in a mouse model of depression

Takashi Iwai1, Yu Matsuzawa1, Honoka Nakajima1, Shigeto Hirayama2, Misa Oyama1, Shun Watanabe1, Hideaki Fujii2, Mitsuo Tanabe1 (1.Laboratory of Pharmacology, school of Pharmacy, Kitasato university, 2.Laboratory of Medicinal Chemistry, school of Pharmacy, Kitasato university)

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