Session Details

[1P]Neuroanatomy, Neurophysiology, Neuronal cell biology Neurological disorders, Neuropathophysiology, brain inflammation

Mon. Mar 17, 2025 5:40 PM - 6:40 PM JST
Mon. Mar 17, 2025 8:40 AM - 9:40 AM UTC
Exhibition Hall

[1P-108]Effects of Postnatal Sleep Restriction on the Development of Inhibitory Neurons and Perineuronal Nets in the Mouse Cerebral Cortex

Hiroshi Ueno1, Eriko Kitano2, Sachiko Mori2, Yu Takahashi2, Takeshi Ishihara2 (1.Dep Med Tech, Kawasaki Univ of Med Welf, 2.Dep Psych, Kawasaki Med Sch)
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[1P-109]SENP2-mediated N-terminal truncation of α-Synuclein in Lewy pathology propagation

Katsutoshi Taguchi1, Yoshihisa Watanabe2, Masaki Tanaka1 (1.Dept. of Anatomy and Neurobiology, Kyoto Prefectural Univ. of Med., 2.Dept. of Basic Geriatrics, Kyoto Prefectural Univ. of Med.)
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[1P-110]4-Phenylbutyric acid improves the abnormal social behavior in autism spectrum disorder model.

Koichi Kawada1,2, Seisuke Mimori2, Kyosuke Uno1, Nobuyuki Kuramoto1 (1.Setsunan Univ., 2.Chiba Inst. Sci.)
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[1P-111]Deficiency of neuronal cathepsin D in adult mice results in neurodegeneration due to lysosomal insufficiency

Shun Mitsui1, Junji Yamaguchi1,2, Chigure Suzuki1, Isei Tanida1, Yasuo Uchiyama1 (1.Institute for Diseases of Old Age, Juntendo Univ Grade Sch Med., 2.Laboratory of Morphology and Image Analysis, Juntendo Univ Grade Sch Med.)
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[1P-112]Electrophysiological analysis of cortical neurons differentiated from iPS cells derived from patients with NEDAMSS disorder

Teruyuki Fukushima1, Inoue Ken-ichi2, Sohma Ryoichi2, Yamauchi Shinobu3, Inoue Haruhisa4, Kansaku Kenji1 (1.Department of Physiology, Dokkyo Medical University School of Medicine, 2.Center for Advanced Medical Science Research, Dokkyo Medical University School of Medicine, Japan., 3.Department of Legal Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan., 4.Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.)
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[1P-113]Oxygen-glucose deprivation induces lipid droplet formation in PC12 cells

Shin Kikuchi, Keisuke Murata, Sunshi Natsuyama, Nobuhiro Wada, Yuki Ohsaki (Sapporo Medical University)
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[1P-114]Depression-like behavior in a mouse model of olfactory dysfunction involves polarization to M1-type microglia in the hippocampus

Kohei Takahashi1, Minoru Tsuji1, Osamu Nakagawasai2, Soh Katsuyama3, Kazuya Miyagawa1, Kazuhiro Kurokawa1, Atsumi Mochida-Saito1, Hiroshi Takeda4, Takeshi Tadano2,5 (1.Department of Pharmacology, School of Pharmacy, International University of Health and Welfare, 2.Division of Pharmacology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 3.Division of Clinical Pharmacology and Pharmaceutics, Nihon Pharmaceutical University, 4.Research Administration Office, International University of Health and Welfare, 5.Department of Environment and Preventive Medicine, Graduate School of Medicine Sciences, Kanazawa University)
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[1P-115]α2 adrenergic receptor antagonists reduce passive stress coping in postpartum female mice

Yoshikage Muroi, Ikuko Horie, Ishii Toshiaki (Obihiro University of Agriculture and Veterinary Medicine)
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[1P-116(ST05-16)]Maternal hypothyroidism during the fetal and neonatal periods causes behavioral abnormalities in mouse offspring

Shiho Mima1,2, Atsuko Hayata-Takano1,3,4, Shunsuke Tomita5, Misaki Iwahashi1,3,4, Keishi Ishida5, Daisuke Matsumaru5, Tsuyoshi Nakanishi5, Kazuhiro Takuma1,3,4 (1.Department of Pharmacology, Graduate School of Dentistry, Osaka University, 2.Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 3.United Graduate School of Child Development, Molecular Research Center for Children’s Mental Development, Osaka University, 4.Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka, 5.Laboratory Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University)
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[1P-117]Expression of midnolin, a genetic risk factor for Parkinson's disease, is regulated via Gq protein-coupled receptors

Ikuo Norota1, Yusuke Zuiki1, Ayano Chiba1, Jiro Ogura2, Hiroaki Yamaguchi2, Mikako Nagashima1, Kuniaki Ishii1, Yutaro Obara1 (1.Department of Pharmacology, School of Medicine, Yamagata University, 2.Department of Pharmaceutical Sciences, School of Medicine, Yamagata University)
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[1P-118]Effects of non-neuronal cells on alpha-synuclein aggregates-induced neurotoxicity in the central and enteric nervous system

Ikuko Miyazaki1, Kaori Masai1, Chiharu Sogawa2, Norio Sogawa3, Yoshihisa Kitamura4, Masato Asanuma1 (1.Dept. of Med. Neurobiol., Okayama Univ. Grad. Sch. of Med., Dent. and Pharmaceut. Sci., 2.Dept. of Clin. Eng., Fac. of Life Sci., Hiroshima Inst. of Tech., 3.Dept. of Mol. Eng. and Drug Dev. Sci., Grad. Sch. of Oral Med., Matsumoto Dental Univ., 4.Dept. of Pharmacother., Sch. of Pharm., Shujitsu Univ.)
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[1P-119]Neuroprotective effects of differentially expressed Nedd4-binding protein Ndfip1 against methamphetamine-induced neurotoxicity

Masato Asanuma1, Ikuko Miyazaki1, Jean Lud Cadet2 (1.Department of Medical Neurobiology, Okayama UniversityDept. of Med. Neurobiol., Okayama Univ. Grad. Sch. of Med., Dent. and Pharmaceut. Sci., 2.Mol. Neuropsychiat. Section, NIH/NIDA, IRP, U.S.A.)
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[1P-120(ST05-10)]Deletion of CXCL10 in a tauopathy model mouse affects the accumulation of pathogenic tau

Ryohei Uenishi, Rinna Kawata, Masanori Hijioka, Takashi Saito (Nagoya City Univ.)
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[1P-121]Aβ pathology propagates to healthy neurons via neurovascular crosstalk induced by Alzheimer’s Aβ assembly binding to vascular Na+ pump

Tomoya Sasahara1,2, Shoko Hongo3, Mika Ito4, Naomi Takino4, Shin-ichi Muramatsu4, Akiyoshi Kakita3, Minako Hoshi1,5 (1.Department of Brain and Neurodegenerative Disease Research, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, 2.Research & Development Division, TAO Health Life Pharma, 3.Department of Pathology, Brain Research Institute, Niigata University, 4.Division of Neurological Gene Therapy, Jichi Medical University, 5.Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University)
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[1P-122]Investigation of pathophysiological roles of chemokine CCL3 in preclinical Alzheimer's disease model mice

Masanori Hijioka, Kanon Tsuji, Ryohei Uenishi, Takashi Saito (Nagoya City Univ.)
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[1P-123]Analysis of the protective mechanism of YAP in Müller cells against NMDA-induced retinal ganglion cell injury in rats

Toshihide Kashihara, Misaki Hatta, Sae Inoue, Akane Morita, Saori Deguchi, Tsutomu Nakahara (Department of Molecular Pharmacology, School of Pharmaceutical Sciences, Kitasato University)
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[1P-124]Direct evidence for ultrastructures of the α-synuclein-associated synaptic vesicle pool in presynaptic terminals

Chigure Suzuki, Junji Yamaguchi,, Shun Mitsui, Takahito Sanada, Soichirou Kakuta, Isei Tanida, Yasuo Uchiyama (Juntendo.Univ, Disease of Old Age Inst)
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[1P-125(ST06-04)]The unfolded protein response in vascular endothelial cells contribute to functional recovery after brain injury

QIYAN FAN1, Takarada-Iemata Mika1, Tanaka Takashi2, Osamu Hori1 (1.Dept. Neuroanat., Kanazawa Univ., 2.Dept. Rehab., Kumamoto Health Sci. Univ.)
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[1P-126]Analysis of CD38-mediated neuronal cell death in excitotoxicity

Tsuyoshi Hattori, Hiroshi Ishii, Mika Takarada, Nguyen Huong Ly, Osamu Hori (Kanazawa Univ.)
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[1P-127]Gene expression analysis in a mouse model of autism spectrum disorder with sensory hypersensitivity

Haruki Iwai, Tetsuya Goto (Kagoshima University)
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[1P-128(ST06-01)]Cell-type and time-specific activation of the unfolded protein response after intrahippocampal injection of kainate in mice

Huong Ly Nguyen, Dinh Loc Nguyen, Tsuyoshi Hattori, Mika Takarada-Iemata, Hiroshi Ishii, Osamu Hori (Dept. Neuroanatomy, Kanazawa University)
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[1P-129]Interactions between voltage-gated sodium channel Nav1.1 and fibroblast growth factor FGF12

Ikuo Ogiwara, Chengzhu Yin, Atsushi Shimohata, Mie Gangi, Daisuke Kato, Kaneda Makoto (Department of Physiology, Nippon Medical School)
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[1P-130(ST05-08)]Reduced gray matter volume in the posterior insula associated with plasma glucose elevation in tolerance test

Weihang Chen, Akitoshi Ogawa, Takahiro Osada, Toshiki Kogai, Hideyoshi Kaga, Yoshifumi Tamura, Hirotaka Watada, Ryuzo Kawamori, Seiki Konishi (Juntendo University)
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[1P-131]Chronic administration of SYK-623, an inverse agonist of δ opioid receptor, prevents the reduction of diazepam sensitivity in a mouse model of depression

Takashi Iwai1, Yu Matsuzawa1, Honoka Nakajima1, Shigeto Hirayama2, Misa Oyama1, Shun Watanabe1, Hideaki Fujii2, Mitsuo Tanabe1 (1.Laboratory of Pharmacology, school of Pharmacy, Kitasato university, 2.Laboratory of Medicinal Chemistry, school of Pharmacy, Kitasato university)
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[1P-132]Acute systemic administration of clozapine fails to alter the extracellular concentrations of D-serine as evaluated by an in vivo dialysis technique.

Masakazu Umino1,2, Hiroshi Shiraku2, Asami Umino1,2, Kanae Hayakawa2, Yuji Kiuchi1, Toru Nishikawa1,2 (1.Department of Pharmacology, Showa University School of Medicine, 2.Psychiatry and Behavioral Sciences1, Tokyo Medical and Dental University)
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[★1P-133]Identification of astrocyte-secreted axonal regeneration-promoting molecules to restore function in Alzheimer’s disease

Kensuke Hayami, Chihiro Tohda, Ximeng Yang (Toyama university)
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[★1P-134]Electrophysiological analysis of the reward response of dorsal raphe nucleus after stress and chronic antidepressant treatment

Harune Hori1,2, Hinako Morishita1,2, Hisashi Shirakawa1, Hitoshi Hashimoto2, Kazuki Nagayasu2 (1.Kyoto University, 2.Osaka University)
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[★1P-135]Drug Screening for Niemann-Pick Disease Type C Using Neurons Directly Converted from Urine-Derived Cells

Keita Matsumoto1, Maika Itsuno1, Hideyuki Okano2, Sumihiro Maeda1 (1.Department of Physiology, Keio University School of Medicine, 2.Keio Regenerative Medicine Research Center)
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[★1P-136]Midnolin, a genetic risk factor for PD, regulates voltage-dependent Ca2+ channel function in PC12 cells

Kohei Nakamura, Ayano Chiba, Ikuo Norota, Mikako Nagashima, Kuniaki Ishii, Yutaro Obara (Department of Pharmacology, Faculty of Medicine, Yamagata University)
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[★1P-137]The role of microsomal prostaglandin E synthase-1 in aggravation of symptoms in a mouse brain tumor model

Haru Sakano1, Yoshiyuki Hayashi1, Shizuo Akira2, Satoshi Uematsu3,4, Tatsuo Takahashi1, Hisaaki Takahashi1, Yuri Ikeda-Matsuo1 (1.Lab Pharmacol, Dept Clin Pharm, Fac Pharmac Sci, Hokuriku Univ, 2.Laboratory of Host Defense, Immunology Frontier Research Center, Osaka University, 3.Graduate School of Medicine, Osaka Metropolitan University, 4.Institute of Medical Science, University of Tokyo)
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[★1P-138]Establishment of uptake assay for tau-containing extracellular vesicles into cells

Hironori Takagi1, Noriko Isoo1, Takamasa Yoshida1, Naoyuki Iso-O2, Yukiko Hori3, Taisuke Tomita3, Toshihiro Hayashi1 (1.Department of Physiology, Teikyo University School of Medicine, 2.Department of Internal Medicine, Teikyo University Mizonokuchi Hospital, 3.Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, University of Tokyo)
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[★1P-139]Analysis of sleep and electroencephalogram in 15q dupulication mouse model of autism spectrum disorder

Kazuha Azuma1, Fumito Naganuma2, Toru Takumi3, Takeo Yoshikawa2, Masaaki Sato2 (1.Hokkaido University School of Medicine, 2.Department of Neuropharmacology Hokkaido University Graduate School of Medicine, 3.Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine)
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[★1P-140]Does thalamic amyloid precursor protein (APP) contribute to neuroinflammation with aging?

Yukiya Murakami1, Hyuga Takahashi1, Shunta Oba1, Tatsuya Sato1, Kenjiro Ono2, Akiyoshi Kakita3, Takafumi Uchida4, Hirokazu Ohtaki1 (1.Tokyo University of Pharmacy and Life Sciences, 2.Kanazawa Univ., 3.Niigata Univ., 4.Tokyo Kasei Univ.)
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[★1P-141]Laterality of multimodal sensory representation in Alzheimer’s disease model mice.

Yuki Takemoto1, Takuya Hikima1, Kumiko Kawabuchi2, Susumu Setogawa1,3, Yasuhiro Hamataka4, Yoshito Saitoh1, Mikiko Ishikawa1, Chikako Kamiyoshihara1, Takashi Saito5, Hiroki Sasaguri6, Takaomi Saido6, Hiroto Sekiguchi4, Makoto Osanai2, Noriaki Ohkawa1 (1.Dokkyo Medical University, 2.Osaka University, 3.Osaka Metropolitan University, 4.Toyohashi University of Technology, 5.Nagoya city University, 6.RIKEN CBS)
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[★1P-142]Neurobehavioral and histological alterations in mice lacking three genes in the human 3p26.3 locus

Mako Saruta1, Asuka Shindo1, Moka Tsuchiya1, Karin Hosoya1, Asami Oguro2, Eri Segi1 (1.Tokyo university of science, 2.University of Exeter)
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[★1P-143]Different staining properties of monoclonal antibodies against N-terminal residues of Aβ peptide

Kana Araki1,2, Kenta Yamauchi1,2, Ito Shogo1,2, Masato Koike1, Hiroyuki Hioki1,2,3 (1.Dept. Neuroanato., Juntendo Univ. Grad. Sch. Med., 2.Dept. Cell Biol. Neurosci., Juntendo Univ. Grad. Sch. of Med., 3.ept. Multi-Scale Brain Struct. Imaging, Juntendo Univ. Grad. Sch. of Med.)
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[★1P-451]Development of a novel mouse model of irritable bowel syndrome induced by visual and auditory aversive stimuli

Yumi Ode, Toshinori Yoshioka, Mizuki Ou, sayaka kimiki, Daisuke Yamada, Akiyoshi Saitoh (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan,)
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