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Mon. Mar 17, 2025

Tue. Mar 18, 2025

Wed. Mar 19, 2025

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Mechano-sensitive TRPV4 signaling pathway involved in progression of abdominal aortic aneurysm

The aorta is the largest blood vessel in the human body, branching directly from the heart, and is the main trunk tissue in blood circulation. In our super-aging society, preventing, early detection, and treatment of fatal aortic diseases such as aortic aneurysms and dissections, which have been increasing in recent years, is a crucial issue. Recent exciting advancements in high-resolution multi-color imaging technologies and multi-omics analysis methods have elucidated the previously unknown causes and pathophysiological mechanisms of aortic diseases. In this symposium, researchers who are attempting to elucidate the pathophysiology of aortic diseases from novel molecular and cellular perspectives will present their cutting-edge work. We will share the latest findings on the mechanisms maintaining homeostasis through intercellular interactions in aortic tissue. We hope to catalyze insights that discuss future prospects for overcoming these diseases from multiple angles. Ultimately, this symposium endeavors to forge a path towards improved preventative measures, earlier diagnoses, and more effective therapeutic interventions for aortic pathologies.

Molecular Insights into Aortic Disease: New Preventive and Therapeutic Frontiers

APPW2025

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[1S07a-3]Mechano-sensitive TRPV4 signaling pathway involved in progression of abdominal aortic aneurysm

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