General information

Announcements(1)

Program

Sessions

Search presentations

Download PDF for print

Timetable

Mon. Mar 17, 2025

Tue. Mar 18, 2025

Wed. Mar 19, 2025

web_header_en.png

web_icon.png

Profile management

Announcements

Bookmark

Program Type

Login required to view

Password required to view

Presentation Information

Session Details

To browse or post comments, you must log in.

You cannot post comments as it is outside the comment posting period.

This comment has been deleted. You cannot reply to this comment.

A novel in vitro 3D bioprinted liver fibrosis model consisted of human hepatocytes to predict hepatotoxicity, efficacy and MOA of potential therapeutic reagent for steatotic liver disease

Joint Session : The Japanese Society for Alternatives to Animal Experiments

Based on the 3Rs and animal alternative methods, technological innovations in human biology are occurring by using New Approach Methodologies, such as human tissues, differentiated cells from human iPS cells, organoids, organ chips, and 3D printing. In addition, the FDA Modernization Act 2.0 has been issued to promote human cell-based evaluation systems for pharmaceutical drugs instead of traditional animal studies. In this symposium, we will discuss strategies to apply human cells for understanding human organ biology, drug development and regenerative medicine. We hope to provide an opportunity to deepen our understanding of human biology by discussing cutting-edge findings from the perspectives of industry, government, and academia. This would allow participants to promote understanding of human biology in the scientific communities, such as alternative methods and human tissues, as well as issues and future prospects.

New trend of human biology using human tissue models

APPW2025

Presentation Information

[1S14m-5]A novel in vitro 3D bioprinted liver fibrosis model consisted of human hepatocytes to predict hepatotoxicity, efficacy and MOA of potential therapeutic reagent for steatotic liver disease

Login required to view

Comment