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Mon. Mar 17, 2025

Tue. Mar 18, 2025

Wed. Mar 19, 2025

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Partial reprogramming of senescent cells ameliorates aging-associated diseases.

Sponsored by : Transformative Research Areas (B) "Aging revival"/ Transformative Research Areas (B) "Resilience Biology"

Aging clock progression diminishes biological resilience, leading to the systemic decline in physiological functions. Recent findings have accumulated experimental evidence suggesting that aging is controlled by epigenomic information, a blueprint that determines how genes work. In addition, experimental evidence suggests that the cellular resilience to stress is already determined at the stage prior to the reception of stimuli. In this symposium, we would like to present our research findings on “the revival mechanism of aging clock" and “the maintenance of cellular resilience to stress", and discuss the significance of confronting “irreversible" life processes and the possibility of controlling and/or reversing them. This symposium is a joint symposium of “Elucidation of Aging Clock Revival Mechanism" and “Resilience Biology", both of which are funded by Grant-in-Aid for Transformative Research Areas (B), and aims to discover new universality of living things from hot topics in both fields.

Defying irreversible life processes

APPW2025

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[3S16a-3]Partial reprogramming of senescent cells ameliorates aging-associated diseases.

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