Session Details
[1P]Ion channels, Receptors, Transporters
Mon. Mar 17, 2025 5:40 PM - 6:40 PM JST
Mon. Mar 17, 2025 8:40 AM - 9:40 AM UTC
Mon. Mar 17, 2025 8:40 AM - 9:40 AM UTC
Exhibition Hall
[1P-184]A novel binding site between the voltage-dependent calcium channel CaV1.2 subunit and beta2 subunit discovered using a new analysis method for protein-protein interactions
agnieszka murakami, minami abe, nagatomo katsuhiro, Hiroshi Kouda, Yasutaka Niwa, ○manabu murakami (Dept. Pharmacol. Hirosaki Univ.)
[1P-185]Construction of an assay for orphan receptor GPR176 activity
○Yasuo Okamoto, Yasuhiro Takenouchi, Keisuke Kitakaze, Hironobu Ishimaru, Kazuhito Tsuboi (Kawasaki Medical School, Department of Pharmacology)
[1P-186]Effects of riboflavin-deficiency on NaCl intake behavior
○Toshiaki Yasuo, Shusuke Iwata, Takeshi Suwabe, Shinpei Takahashi, Noritaka Sako (Department of Oral Physiology, Asahi University School of Dentistry)
[1P-187]Effects of capsaicin on the chorda tympani nerve responses and the ingestive behavior for five basic tastes in mice.
○Shusuke Iwata1, Shinpei Takahashi1, Toshiaki Yasuo1, Takashi Suwabe1, Keiko Yasumatsu2, Noritaka Sako1, Yuzo Ninomiya3,4 (1.Dept. Oral Physiol. Asahi Univ. Sch. Dent., 2.Tokyo Dental Junior Collegue., 3.Dept. of Oral Physiol., Grad. Sch. of Med., Dent., and Pharm. Sci., Okayama Univ., 4.Monell Chemical Senses Center)
[1P-188]Increased protein expression of neonatal hyperparathyroidism-associated TRPV6 calcium channel variants
○Yoshiro Suzuki, Soshi Otani, Masaki Hayashi, Ryunosuke Fujita, Hiroho Saito, Katsumi Nakajima (Department of Physiology, Iwate Medical University)
[1P-189]Voltage Sensors of Na+ Channels Dissociate from the Pore Domain and Form Inter-Channel Dimers in the Resting State: Implications for Cooperative Activation
○Ayumi Sumino1,2, Takashi Sumikama1, Mikihiro Shibata1,2, Katsumasa Irie3 (1.WPI-NanoLSI, Kanazawa University, 2.Institute for Frontier Science Initiative (Infiniti), Kanazawa University, 3.Department of Biophysical chemistry School of Pharmaceutical Science, Wakayama Medical University)
[1P-190]Distinct roles of protons and chloride during glutamate transport into synaptic vesicles in living neurons
○Hiroyuki Kawano1, Tomofumi Yoshida1, Yoshihiro Egashira2, Yasunori Mori3, Shigeo Takamori1 (1.Doshisha University, Graduate school of Brain science, 2.Osaka Medical and Pharmaceutical University, 3.University of Yamanashi)
[1P-191]GYY4137, a slow H2S releaser, and Lawesson’s reagent, a sulfurizer, slowly reduce Cav3.2 T-type calcium channel activity: opposite effects to the sulfide-induced rapid and noticeable enhancement of Cav3.2 activity
○Fumiko Sekiguchi1, Yuina Sakamoto1, Yuki Nango1, Yoshihito Kasanami1, Genzoh Tanabe2, Atsufumi Kawabata1 (1.Lab. Pharmacol. Pathophysiol., Fac. Pharm., Kindai Univ., 2.Lab. Pharm. Org. Chem., Fac. Pharm., Kindai Univ.)
[1P-192]Evaluating the Differential Effects of TRPM2 Inhibitory Drugs and Analogs on TRPM2 and Its Cys549 Variant
○TIANYU MIAO (Kyoto Univ.)
[1P-193]Molecular analysis for sugar selectivity and open mechanism of the insect fructose sensor ion channel BmGr9
○Kazuyo Kamitori1,2, Shunsuke Takahashi1, Kasumi Kozai1, Yuichiro Fujiwara1,3 (1.Laboratory of Molecular Physiology and Biophysics, Faculty of Medicine, Kagawa University, 2.International Institute of Rare Sugar Research and Education Kagawa University, 3.Physiology and Biophysics, Graduate School of Biomedical and Health Sciences, Hiroshima University)
[1P-194]OAT10 serves as an apical urate re-absorber in the kidney: physiological and pharmacological impacts
○Yu Toyoda1,2, Tappei Takada2, Yusuke Kawamura1, Akiyoshi Nakayama1, Keito Morimoto2, Seiko Shimizu1, Nariyoshi Shinomiya1, Yasushi Kobayashi1, Hirotaka Matsuo1 (1.National Defense Medical College, 2.The University of Tokyo Hospital)
[1P-195]Repetitive Transcranial Magnetic Stimulation (rTMS) induced NET (norepinephrine transporter) and NET b regulate the expression of caspases mRNA and protein activities on PC12 cells
○Tetsurou Ikeda1, Chikao Morimoto2 (1.Aomori University, 2.Juntendo University)
[1P-196]Muscarinic receptors activate non-selective cation channels and increase the excitability of fusiform cells of the mouse dorsal cochlear nucleus.
○Tomohiko Irie, Rei Yamada (Department of Physiology, Kitasato University School of Medicine)
[1P-197]AI-based approach to identification of residues underlying substrate specificity of voltage-sensing phosphatase (VSP) distinct from PTEN
○Natsuki Mizutani1,2,3, Teppei Niide4, Atsushi Nakagawa1, Hiroshi Shimizu4, Yasushi Okamura2 (1.Institute for Protein Research, Osaka Univ., 2.Integrative Physiol., Grad. Sch. Med., Osaka Univ., 3.Research Fellow of JSPS, 4.Bioinformatic Eng., Grad. Sch. Inf. Sci. and Tech., Osaka Univ.)
[1P-198]A comprehensive analysis of the DII-S4 movement in Two-pore channel 3
○Takushi Shimomura1,2, Yoshihiro Kubo1,2 (1.National Institute for Physiological Sciences, 2.The Graduate University for Advanced Studies)
[1P-199(ST09-04)]Effect of Charge Movement in the Ion Binding Processes of the Na/Ca Exchanger Current Voltage Dependency
○Shaocong Ou1, Zhongyang Xiao2, Keika Oyama1, Masaaki Furukawa1, Yuttamol Muangkram1, Yukiko Himeno1, Akira Amano1 (1.Graduate School of Life Sciences, Ritsumeikan University, 2.College of Life Sciences, Ritsumeikan University)
[1P-200]Role of monocarboxylate transporter 1 (MCT1) in cerebral ischemic injury
○Yuri Hirayama, Naohiko Anzai (Dept. Pharmacol., Grad. Sch. Med., Chiba Univ.)
[1P-201(ST09-05)]Constitutive activities of EP4 receptors that contributes to cell proliferation
○Shunya Yanagawa1, Akihito Mitsuzono1, John W. Regan2, Keijo Fukushima1, Hiromichi Fujino1 (1.Tokushima Univ., 2.The Univ. of Arizona)
[1P-202]Bi-phasic regulation of THIK-1 channel by adenosine receptor A1R dependent on the agonist dose
○Michihiro Tateyama1,2, Yoshihiro Kubo1,2 (1.Div. Biophysics and Neurobiology, NIPS, 2.Dept of Advanced Sciences, SOKENDAI)
[1P-203]Elucidation of the Inhibitory Mechanism of P-glycoprotein Inhibitor Elacridar
○Norie Hamaguchi1,2,4, Naruhiko Adachi3, Toshio Moriya3, Masato Kawasaki3, Satoshi Yasuda4, Naohiko Anzai2, Toshiya Senda3, Satoshi Ogasawara4, Takeshi Murata4 (1.Grad. Sch. of Med. and Pharm. Sci, Chiba Univ., 2.Grad. Sch. of Med, Pharm, Chiba Univ., 3.SBRC. IMSS. KEK., 4.Dept. of Chem., Grad. Sch. of sci., Chiba Univ.)
[1P-204(ST09-14)]Effects of Piezo1 activation on the inflammatory response in primary cultured rat chondrocytes.
○Yuka Tanaka, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Morioka (Dept. Pharmacol., Grad. Sch. Biomed. Health Sci., Hiroshima Univ.)
[1P-205]The new insights of the underlying mechanisms in cooling-induced contraction of urinary bladder
○Shunichi Kajioka1, Tatsunori Okada2, Tomoko Maki2, Ayami Okabe2, Kenichi Kato2, Masatoshi Eto2 (1.International University of Health and Welfare, 2.Kyushu Univ.)
[★1P-206]The Effect of Hypoxia on Cerebral Vascular Endothelial Cells Through Orai1
○Noriyuki Furukawa1, Yu Iida1,2, Mio Mochizuki1, Kagemichi Nagao1,2, Akane Nagasako1, Yoshihiro Ishikawa3, Masanari Umemura1 (1.Cardiovascular Research Institute (CVRI), Yokohama City University Graduate School of Medicine, 2.Department of Neurosurgery, Yokohama City University Graduate School of Medicine, 3.Yokohama City University President)
[★1P-207]Exploring the key module involved in conformational change in type 1 ryanodine receptor by cryo-EM and MD simulation
○Mahiro Yamanashi, Takashi Murayama, Takashi Sakurai, Takuya Kobayashi (Juntendo Univ.)
[★1P-208]Comparison of effects of PGF2α and four glaucoma drugs on human FP receptors
○Tomofumi Harada1, Hatate Shibahara1, John W. Regan2, Keijo Fukushima1, Hiromichi Fujino1 (1.Tokushima Univ., 2.The Univ. of Arizona)
[★1P-209]Real-time detection of fructose concentration utilizing structural changes in an insect gustatory receptor
○Kazuma Matsuoka1, Akira Kawanabe1,3, Kazuyo Kamitori1,2, Yuichiro Fujiwara1,3 (1.Laboratory of Molecular Physiology & Biophysics, Faculty of Medicine, Kagawa University, 2.International Institute of Rare Sugar Research and Education, Kagawa University, 3.Physiology and Biophysics, Graduate School of Biomedical and Health Sciences, Hiroshima University)
[★1P-210]Molecular identification of the K+ channels involved in the cell water excretion by Boi-ogi-to
○Taro Suzuki1, Rin Okuma1, Kento Kuroko1, Haruna Saito1, Shuntaro Mori1, Shotaro Kato2, Ayako Sakai3, Kaori Sato-Numata3, Yasunobu Okada3,4,5, Tomohiro Numata3 (1.School of Medicine, Akita University, 2.Akita University Hospital, 3.Department of Integrative Physiology, Graduate School of Medicine, Akita University, 4.National Institute for Physiological Sciences, 5.Department of Physiology, School of Medicine, Aichi Medical University)