Session Details
[3S08a]Investigating, understanding, and protecting the pathology of cardiac, skeletal, and smooth muscle-related diseases
Wed. Mar 19, 2025 1:40 PM - 3:30 PM JST
Wed. Mar 19, 2025 4:40 AM - 6:30 AM UTC
Wed. Mar 19, 2025 4:40 AM - 6:30 AM UTC
Room 8
Oranizers :Lin Kurahara (Department of Cardiovascular Physiology,Faculty of Medicine, Kagawa University) and Tsuyoshi Shuto (Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University)
This symposium will feature the latest findings from researchers from domestic and international academic societies who are leading the pathophysiology of cardiac, skeletal and smooth muscle-related diseases. In particular, we aim to deepen our understanding of novel therapeutic target molecules for cardiovascular diseases such as age-related arteriosclerosis and heart failure, strategies for maintaining skeletal muscle homeostasis, treating skeletal muscle degeneration and preventing sarcopenia, and the relationship between abnormal smooth muscle proliferation and cellular senescence seen in pulmonary hypertension. We hope to deepen discussions on the possibilities and prospects of single-cell analysis of muscle cells, data science and new drug discovery modalities from the perspectives of morphology, physiology, pharmacology, regenerative engineering and preventive medicine.
[3S08a-1]Therapeutic targets for treating age-related cardiovascular diseases
○Yong Zhang, Xin Liu, Lei Jiao, Jiamin Li, Ying Zhang (College of Pharmacy, Harbin Medical University, Harbin, China)
[3S08a-2]Regenerative engineering approaches for the treatment of muscle degeneration to inhibit fatty infiltration
○Takayoshi Otsuka1,2, Shemshaki Nikoo2, Kan Ho-Man2, Mengsteab Paulos2, Barajaa Mohammed2, Lakshmi Nair2, Laurencin Cato2 (1.Department of Neuroscience of Disease, Brain Research Institute, Niigata University, 2.The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut)
[3S08a-3]Role of the microenvironment in muscle adaptation and therapeutic strategy for age-related sarcopenia
○Yusuke Ono1,2 (1.Kumamoto University, 2.Tokyo Metropolitan Institute for Geriatrics and Gerontology)
[3S08a-4]Proposal of new treatment agents for pulmonary hypertension, targeting the signals of smooth muscle proliferation and angiogenesis
○Lin Hai Kurahara1, Gaopeng Li1, Xiaodong Li1, Kaori Ishikawa2, Ryo Ishikawa3, Kazufumi Nakamura4, Katsuya Hirano1 (1.Dept. Cardiovasc. Physiol., Faculty of med., Kagawa University, 2.Dept. General Med., Kagawa Univ. Hospital, 3.Dept. Diagnostic Pathology, Kagawa Univ. Hospital, 4.Center for Advanced Heart Failure, Okayama University Hospital)